Liquid Chromatography – Products

This work describes the migration of a method from legacy HPLC systems to the modern Alliance™ iS HPLC System.

This study demonstrates using a previously reported HPLC method for the analysis of using the Alliance iS HPLC System. The method uses a preformulated mobile phase, wash solvent, and standards from Waters™ (Waters Beverage Analysis Kit).

Here, we will demonstrate the ability to achieve the same quantitative results on legacy and newer HPLC systems. The legacy Alliance e2695 System and the Alliance iS HPLC System were chosen for method migration

This application note will discuss the challenges of this method and compare the results obtained across a number of different HPLC systems.

This study was performed to explore how the difference in autosampler design between the Alliance iS HPLC System and Vendor X HPLC System can affect the results of a HILIC method analysis when varying wash solvent compositions are utilized.

This study will demonstrate the analysis of atorvastatin according to the USP monograph using the Alliance iS HPLC System.

This work describes a single high performance liquid chromatography (HPLC) method for the analysis of Aspirin active pharmaceutical ingredient (API) and six associated related substances.

In this application note, we will look at how the Alliance iS HPLC System has many important elements that will help to achieve a successful method migration.

In this application note, carryover of chlorhexidine will be evaluated on a variety of HPLC systems across various vendors. In addition, mitigation strategies, namely implementation of needle wash and/or extending washing will be explored as well.

Method migration, or moving a method from one high-performance liquid chromatography (HPLC) system to another, is routine practice in many regulated laboratories, where there may be a variety of HPLC systems from different vendors and different models in a single lab.