Liquid Chromatography – Webinars and Online Events

This on-demand webinar explores how an electron-activated dissociation (EAD)-based LC-MS workflow provides a comprehensive approach to glycan analysis, enabling more accurate profiling and streamlined processes.

This webinar explores the implementation of a liquid chromatography mass spectrometry (LC-MS) workflow for peptide mapping to investigate and track these PTMs.

Our expert speakers will also discuss how to apply the Oligo Analysis Accelerator for OpenLabs CDS to your oligonucleotide therapeutic testing, helping you to optimize synthesis and purification.

Clinical blood analysis is crucial for monitoring health and diagnosing diseases, with blood-based biomarkers playing a key role.

In this webinar, our expert speaker will discuss how HPLC-MS can detect a wide range of allergens in a single run, reducing the time and effort involved in food analysis.

Biomonitoring of toxicants like pesticides and PFAS in humans is essential for understanding how chemical exposure affects our health, yet chemical coverage is currently limited with targeted LC-MS approaches.

This webinar provides essential strategies and technologies for achieving error-free method transfers, scaling and operation.

Join us for an exclusive event where Agilent will showcase cutting-edge biopharma solutions. Discover Agilent’s comprehensive portfolio for genomics, spanning drug discovery, quality control and manufacturing. Explore the use of Seahorse for interpreting cellular bioenergetic metabolism and xCELLigence for robust potency assays.

Advances in monoclonal antibody (mAb) engineering have led to additional challenges in the purification of these modalities, including high levels of aggregates. Ion exchange chromatography is often not sufficient to achieve purity targets meaning hydrophobic interaction chromatography (HIC) and mixed-mode resins are needed as orthogonal tools. These technologies can be implemented in flow-through mode allowing for high loadings and fast processing times, making them well-suited for large-scale implementation.

This webinar highlights three case studies that illustrate how novel chromatographic tools can improve the purification process for complex therapeutics by reducing the levels of aggregates and host cell proteins (HCPs) and effectively clearing retroviruses.

Accurate and precise measurement of pharmaceutical drugs in complex matrices can be challenging due to the presence of matrix contaminants. To ensure the highest levels of accuracy and precision, it is imperative to use highly robust analytical techniques. Triple quadrupole mass spectrometers are widely used in quantitative bioanalysis because of their stable analytical performance over an extended period. Here, exceptional sensitivity and stability were demonstrated to support bioanalytical workflows in high-throughput laboratories.