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Liquid Chromatography – Webinars and Online Events

Masterclass: Upgraded MAM With EAD content piece image
Webinar

Masterclass: Upgraded MAM With EAD

On-Demand
Watch this webinar to discover an EAD platform method that enables confident and accurate identification, accurately quantify and monitor quality attributes
and can do all the above with MAM in a single injection.
Handle with Care: Ensuring LNP Quality for Better Genetic Medicines content piece image
Webinar

Handle with Care: Ensuring LNP Quality for Better Genetic Medicines

On-Demand
Speaking at the Advances in Drug Discovery & Development 2022 online symposium, Adam Crowe from SCIEX discussed how an ionizable lipid was analyzed with liquid chromatography coupled with mass spectrometry.
The Latest Workflows for Gene Therapy Analysis content piece image
Webinar

The Latest Workflows for Gene Therapy Analysis

On-Demand
During this webinar, you will understand how capillary electrophoresis (CE) and LC-MS are being used to ensure vaccine and cell and gene therapy product quality. We will discuss how LC-MS is being used to identify impurities present in lipid nanoparticle (LNP) vaccines that have been found to deactivate mRNA. We will also cover how CE is being used in viral vector production to ensure product quality.
In-Depth Analysis of Lipids by Electron Activated Dissociation content piece image
Webinar

In-Depth Analysis of Lipids by Electron Activated Dissociation

On-Demand
Analyzing lipids can be a challenge but combining tandem mass spectra obtained from electron-activated dissociation (EAD) can make the process easier. In fact, over 1000 lipids can be analyzed by ballistic data-dependent acquisition liquid chromatography-mass spectrometry. This methodology produces a large number of high-quality EAD fragmented spectra, making annotation the limiting factor, but combinatorial fragmenters can be used to effectively solve this challenge.

In this webinar, we demonstrate how the ZenoTOF 7600 system can be used in a workflow for the routine analysis of lipids that enables the resolution of sn-isomerism and double bond positions from high-throughput EAD mass spectrometry data.
Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography Coupled with Mass Spectrometry content piece image
Webinar

Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography Coupled with Mass Spectrometry

On-Demand
Speaking at Proteomics & Metabolomics 2022, Prof. Gérard Hopfgartner and
David Ruskic, PhD from University of Geneva, presented their talk on direct analysis of complex biological fluids such as, plasma and urine with liquid chromatography.
Speed, Scale, Specificity: How Next-Generation Mass Spectrometry is Transforming Small Molecule Biomarker Profiling content piece image
Webinar

Speed, Scale, Specificity: How Next-Generation Mass Spectrometry is Transforming Small Molecule Biomarker Profiling

On-Demand
Speaking at Proteomics & Metabolomics 2022, Mohit Jain from Bruker, presented their talk on small molecule biomarkers in drug development.
New Oligonucleotide Characterization Workflows With LC-MS/MS content piece image
Webinar

New Oligonucleotide Characterization Workflows With LC-MS/MS

On-Demand
In this webinar you will gain a deeper understanding of how to measure oligonucleotide in a robust environment with high isotopic fidelity mass spectrometry and much more.
Refine Size Exclusion Analysis of Proteins Using Multi-Angle Light Scattering and Mass Spectrometry content piece image
Webinar

Refine Size Exclusion Analysis of Proteins Using Multi-Angle Light Scattering and Mass Spectrometry

On-Demand
Biotherapeutics such as monoclonal antibodies and other proteins are routinely analyzed by size exclusion chromatography (SEC) to detect high and low molecular weight impurities (aggregates or fragments). Predominantly, UV absorbance is used for detection. However, advanced detection technologies namely multiangle light scattering (MALS) and mass spectrometry (MS) better characterize proteins and reveal species hidden in UV chromatograms.

This webinar will explain the different detection methods and their results. Special emphasis will be placed on the higher requirements for size exclusion columns preceding advanced detection methods.
Complex Matrices: How the PerkinElmer QSight LC/MS/MS Can Help Tackle the Toughest Samples content piece image
Webinar

Complex Matrices: How the PerkinElmer QSight LC/MS/MS Can Help Tackle the Toughest Samples

On-Demand
Speaking at the Advances in Food & Beverage Analysis 2022, PerkinElmer's Derek Mattern delivered his talk on the Q Sight LC/MS/MS and how it can tackle the toughest samples.
Exploring the Lipid Landscape and Unravelling Isomers content piece image
Webinar

Exploring the Lipid Landscape and Unravelling Isomers

On-Demand
This webinar explores the use of high-resolution ion mobility performed on the MOBIE platform for the characterization of different lipid classes starting from phosphatidylcholines and gangliosides.
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