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Neurogenomics – News and Features

A purple human brain.
News

Scientists Map the Genetic Regulatory Elements of the Brain

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders.
A girl sitting on a chair looking out a window.
News

PTSD and Depression Have Shared and Distinct Brain Molecular Dysregulations

McLean Hospital researchers uncovered both shared and distinct molecular changes across brain regions, genomic layers, cell types and blood in individuals with posttraumatic stress disorder (PTSD) and major depressive disorder (MDD).
Neurodegeneration.
News

Clinical Trial Offers Promising Results for Alzheimer’s

A team evaluated a new drug for enhancing the brain’s resilience to changes driven by Alzheimer’s, showing promising results for patients with mild to moderate forms of the disease in its first human trial.
Mouse microglia flagged in red, the nuclei of other cells shown in blue and Hes1 activation shown in white.
News

Immune Reactions in Pregnant Mice Trigger Permanent Changes in Juvenile Brains

The immune response to viral infection during pregnancy affects the development of the unborn offspring, a new study in mice reveals.
A close up of someone's legs while running.
News

Exercise May Slow Cognitive Decline During Aging

University of Queensland research has found exercise can help prevent or slow cognitive decline during aging.
Cancer cells.
News

Mouse Study Explores Why Glioblastoma Treatment May Work Better in the Morning

Glioblastoma is an aggressive brain cancer that has no cure. A recent chart study of patients with glioblastoma found that taking chemotherapy in the morning was associated with a three- to six-month increase in median survival.
A purple human brain.
News

Gene Delivery Vehicle Shows Promise for Human Gene Therapy

Scientists have engineered an adeno-associated virus (AAV) that efficiently crosses the blood-brain barrier in human cell models and delivers genes throughout the brain in humanized mice.
Neurodegeneration.
News

Researchers Identify Symptom-Free Alzheimer’s Patients

Researchers looked at brains from the Netherlands Brain Bank. The team found a subgroup of people who had Alzheimer’s disease processes in their brains, but did not show any clinical symptoms while alive.
Neurons that are degenerating.
News

Rapid Cell Aging Discovered in Certain Brain Cells Linked to Alzheimer’s

Engineers at the University of California San Diego have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer’s disease.
The shape of a brain in bright star shapes.
News

Engineers Create a New Method To Detect Light Deep in the Brain

A new method to label cells deep within the brain has been developed.
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