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Neurogenomics – News and Features

A purple human brain.

New Biomarkers Could Help Diagnosis of Schizophrenia in Rare Genetic Disorder

A recent study led by UC Davis Health researchers provides new insights into the molecular changes linked to the rare genetic condition 22q11.2 deletion syndrome, or 22q.
Dr. Sarah Teichmann standing next to a building and pond.

From School Science Club to Cell Atlasing With Dr. Sarah Teichmann

In this interview, Dr. Sarah Teichmann shares insights into her research interests, the goals and progress of the HCA to date, as well as her thoughts on how women can begin and build successful careers in science.
A bright image depicting neuronal connections.

BARSeq Reveals the Brain Is Like a Pointillism Painting

BARseq, a high-throughput sequencing method, allows scientists to read and localize RNA barcodes in situ. In a new Nature study, researchers from the Allen Institute for Brain Science applied BARseq to explore how peripheral inputs shape the cellular composition of cortical neurons.
A person sits next to a pile of photographs.

Memory Formation Mechanism Requires DNA Flexibility

Researchers have uncovered a novel mechanism underlying memory formation that involves rapid changes to DNA structure.
A girl sat alone in a room looking out a window.

Study Identifies Genetic Roots of PTSD

Findings from the largest genetic study of PTSD to date could help explain why only some people develop the condition after experiencing trauma.
High magnification micrograph of microglia cells stained with Rio-Hortega's method (silver carbonate). This type is the ramified or resting microglia that appears in normal brain tissue.

Mobilizing Microglia in the Fight Against Alzheimer’s Disease

Recently approved Alzheimer's drugs work by tagging amyloid plaques for clearance by the brain's microglia. Washington University School of Medicine in St. Louis researchers are developing an alternative approach, using a homemade antibody to directly mobilize microglia.
A scientist in a white lab coat helps a person with Down syndrome into a brain scan machine.

Alzheimer’s Starts Earlier and Progresses Faster in People With Down Syndrome

A new study revealed that Alzheimer's disease starts earlier and progresses faster in people with Down syndrome, which could have important implications for their treatment and care.
Brain cells under a microscope.

Lewy Bodies in Brain Cells Reveal Parkinson’s Disease Insights

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson’s disease and some dementias.
Double helix structure of DNA.

Single-Cell Atlas Sheds Light on Pristina leidyi's Regenerative Capabilities

An international team of scientists has published the first single-cell atlas forPristina leidyi (Pristina), a segmented annelid with extraordinary regenerative abilities that has fascinated biologists for more than a century.
Vitamin A-containing foods.

Vitamin A and Human Health: What’s the Latest Research?

Here, we highlight some of the latest advancements in vitamin A research working to address its effects on human health.