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Neurogenomics – News and Features

Imagery of a head represented by tree trunks.

Long-Term Memory Formation Requires Nerve Cell Damage

A new study published in Nature puts a different spin on inflammation’s role in the brain, one that could have implications for drugs that target inflammatory pathways.
Neurons connecting.

New Research Identifies Key Driver of Myelination in the Brain

New research from scientists at the Wu Tsai Neurosciences Institute at Stanford University has identified a key driver of myelination, the formation of protective fatty sheaths around nerve fibers.
Cells labelled with bright green and blue dye.

Molecular Links Between ALS and FTLD Cognitive Disorders Exposed

Gene expression patterns in the brain’s motor and frontal cortex reveal many shared cellular and molecular similarities between ALS and FTLD that could be targeted for potential treatment.
Histology of ovaries from healthy mice vs. mice without Usp7 gene.

Researchers Uncover Protein Networks in Female Mouse Reproduction

Scientists have found that while a protein called FOXL2 plays a role in embryonic development, it regulates the activity of many more genes after birth.
A 3D model of a human brain.

Study Reveals Key Role of Immune Cells in Alzheimer's Disease

The Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain immune cells, microglia.
Cancer cells.

Targeting Cancer-Fueling Proteins Shows Potential for Treating Aggressive Leukaemia

Researchers have found a new way to potentially treat one of the most common forms of acute lymphoblastic leukaemia. The study was able to kill leukaemia cells in the lab and stop cancer cells from growing.
Orange and white capsules coming out of a plastic pill bottle.

Existing Drug Shows Potential for Treating Nerve Injuries in Mouse Study

Recently, a research team led by City University of Hong Kong (CityU) neuroscientists found that metaxalone treatment accelerates nerve repair and function recovery comparable to immediate treatment, offering a highly relevant clinical strategy.
Dr. Amy Butler standing in front of a flight of stairs.
Industry Insight

Women in Science: From Lab to Leadership

In this opinion piece, Amy Butler shares her career path from lab to leadership, including how she was able to rise up in the ranks despite being an introvert.
Double helix structure of DNA.

Novel Receptor Function Offers Therapeutic Promise for Fragile X Syndrome

A team of researchers has discovered a novel receptor function that may be used in a therapeutic approach to treatment for Fragile X syndrome.
Neurons degrenerating.

Common Biological Basis Identified in Schizophrenia and Aging

Tightly synchronized genetic changes in two types of brain cells may underlie cognitive impairment in both conditions, offering potential therapeutic clues.