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Next-Generation Sequencing – News and Features

A 3D model of a human brain.
News

RNA Editing Differs in Living vs Postmortem Brains

Researchers from the Icahn School of Medicine at Mount Sinai have shed valuable light on the nuanced functions and intricate regulatory methods of RNA editing, a critical mechanism underlying brain development and disease.
A scientist pipetting into a test tube.
News

Three Extinct Walnut Species Found in Arctic's Ancient Forest

Scientists describe three new, but long-extinct, walnut species on an island above the Arctic Circle. The fossils were discovered further north than any known walnut species, living or extinct.
Mycena epipterygia.
News

Arctic Mushrooms Have the Biggest Fungal Genomes

A study of multiple Mycena mushroom species, also known as “bonnets,” reported in the journal Cell Genomics on June 27 has found that they have unexpectedly large genomes.
Red and blue frog on the ground.
News

Frogs' Light-Sensing Proteins Have Evolved With Surprising Diversity

Opsins are responsible for many biological functions, like regulating circadian rhythms. Research into the evolution of nonvisual opsins in frogs has found that most modern species examined retained a shocking number of these proteins.
Human immune cells (nucleus: blue, cell boundary: red) with Mycobacterium tuberculosis (green) in the collagen hydrogels.
News

New 3D Model Speeds Up TB Drug Testing

Researchers from the Department of Bioengineering (BE), Indian Institute of Science (IISc), have designed a novel 3D hydrogel culture system that mimics the mammalian lung environment.
A cartoon of an intestine with bacteria and a female scientist.
News

Gut Microbiome “Digital Twin” Simulates Personalized Responses to Diet

Short-chain fatty acids (SCFAs) are beneficial molecules created by the bacteria residing in our gut that are closely tied to improved host metabolism, lower systemic inflammation, better cardiovascular health, lower cancer risk, and more.
A gloved hand placing a vial inside an LC-MS instrument.
Article

Mass Spectrometry Imaging in Pharmaceutical Development

In this article, we explore how mass spectrometry imaging technology is evolving into a high-resolution spatial biology toolset to transform drug discovery and development.
Cells.
News

Celiac Drug Shows Promise in Early Trial

A recent study investigated whether a transglutaminase 2 inhibitor has potential as a drug to treat celiac disease. Previous tissue studies have shown that the ZED1227 transglutaminase 2 inhibitor prevents gluten-induced intestinal damage.
Cells.
News

Hematopoietic Stem Cells Age Differently

Researchers at The Jackson Laboratory reveal that hematopoietic stem cells age differently in genetically identical mice, offering new pathways for interventions to preserve health with aging.
A forensic scientist observes a crime scene.
Article

Universal Microbial Network Breaks Down Human Flesh

Technology Networks spoke to the research team behind the discovery of a network of microbes that appear to drive the decomposition of animal flesh to learn more about how the finding could help in modulating decomposition processes.
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