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Next-Generation Sequencing – News and Features

Omid Farokhzad, chair and CEO at Seer.
Industry Insight

Pushing the Boundaries of Biological Discovery in Proteomics

Dr. Omid Farokhzad, chair and CEO at Seer, discusses how to achieve deep, unbiased and scalable analysis of the proteome at speed at ASMS 2024.
A close up of a rice plant.
News

CRISPR Technology Used To Edit Photosynthesis for the First Time

A team from the Innovative Genomics Institute at the University of California, Berkeley (UCB) has produced an increase in gene expression in a food crop by changing its upstream regulatory DNA.
A scientist places test tubes containing blood into a test tube rack.
News

Patients With Schizophrenia Are Three Times More Likely To Have Bartonella DNA in Their Blood

A new study has found that patients diagnosed with schizophrenia or another psychotic disorder are three times more likely to have Bartonella DNA in their blood.
Cancer cells.
News

“Molecular Portrait” Established of Key Pancreatic Cancer Gene

Researchers have established the most comprehensive molecular portrait of the workings of KRAS, a key cancer-causing gene or “oncogene,” and how its activities impact pancreatic cancer outcomes.
A macrophage cell.
News

Macrophages Promote Muscle Healing By Behaving Like Mural Cells

A new study from researchers at Uppsala University establishes that macrophage in the adult ischemic muscle induce a phenotype switch into mural cells to support restoration of functional blood flow and thereby promote healing.
Neurons degenerating.
News

Long-Read Sequencing Identifies RNA Isoforms in Alzheimer’s Patients

Researchers at the University of Kentucky Sanders-Brown Center on Aging are working to develop a pre-symptomatic disease diagnostic tool for Alzheimer’s disease.
Stem cells.
News

Gut Stem Cell Research Reveals Mistaken Cellular Identity

Two independent studies by Columbia scientists suggest that research into the gut’s stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.
Close-up photograph of a person's mouth smiling
News

Opportunistic Bacteria Are More Abundant in the Microbiome of Mouthwash Users

After three months of daily use of an alcohol-based mouthwash, two species of opportunistic bacteria were significantly more abundant in the mouth. These findings provide evidence that mouthwash may have a detrimental effect on the oral microbiome.
A strand of RNA.
News

Novel Method Unveils Cellular Coordination of Gene Transcription

By capturing short-lived RNA molecules, scientists can map relationships between genes and the regulatory elements that control them.
DNA double helix with 5mC and 5hmC methylation modifications indicated.
Industry Insight

Picking Apart the Epigenome To Advance Cancer Research

Both genetic and epigenetic sample information is required to get the full picture. Six-base genome sequencing enables this without need of multiple techniques, laborious downstream data processing or data loss, and cancer research is benefiting.
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