RNA-Seq – News and Features

ETH Zurich researchers have generated over 400 human nerve cell types from stem cells using systematic combinations of morphogens and gene activation. This improves disease modeling for conditions like Alzheimer’s and schizophrenia.

Analysis from the Thrombotic Thrombocytopenia Syndrome Consortium has provided critical insights into the rare but serious condition known as vaccine-induced immune thrombotic thrombocytopenia, which has been linked to certain COVID-19 vaccines.

Salk Institute scientists identified a brain circuit that gives pain its emotional intensity. This CGRP-linked spinothalamic pathway connects to the amygdala, triggering distress and avoidance.

While many patients experience long-term benefits from cancer treatment, some will derive no benefit whatsoever. The study examined RNA sequencing data and clinical outcomes from several prostate cancer clinical trial datasets.

The skeletal muscles of men and women process glucose and fats in different ways, potentially explaining why metabolic diseases manifest differently.

Japanese researchers found that melanin can protect or worsen hereditary hearing loss depending on genetic context. In mice lacking the SLC26A4 gene, pigment buildup caused immune activation and inflammation in the inner ear.

Explore how multiomics research combines genomics, proteomics, and transcriptomics to offer new insights in disease modeling and therapeutic advancements.

A study from Karolinska Institutet reveals that new neurons continue forming in the adult hippocampus, the brain's memory hub. The researchers confirmed the presence of dividing neural progenitor cells across ages 0 to 78.

Researchers have identified a rare cell type and the signaling pathway behind how lung damage from toxins like wildfire smoke or respiratory viruses is repaired.

Researchers have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology, slashing the time needed to do this.