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Single-Cell Analysis – News and Features

Illustration of ovarian cancer present in the female reproductive system.
News

Ovarian Cancer Risks Linked to Genetic Mutations

Researchers have established a living fallopian tube biobank, utilizing cells and tissues donated by patients, which helps scientists study how ovarian cancer begins — cell by cell — directly in human tissue.
A close up of a syringe drawing liquid from a vaccine vial.
News

Dual-Adjuvant HIV Vaccine Offers Strong Protection With One Dose

Researchers have shown that they can generate a strong immune response to HIV with just one vaccine dose, by adding two powerful adjuvants – materials that help stimulate the immune system.
Colorful microbiota and bacteria floating within the intestinal lining, representing the gut microbiome.
Article

Using Next-Generation Sequencing To Understand the Role of the Microbiome in Health and Disease

This article explores how next-generation sequencing has revolutionized microbiome research, enabling comprehensive analysis of microbial communities and their roles in health and disease.
A strand of RNA coils across the image, illustrating RNA sequencing.
News

Single-Cell RNA Sequencing Made 47 Times Cheaper by New Method

A new method combines microscopy with single-cell RNA analysis to make the technique more accessible and scalable, giving researchers an advantage in the numbers game of single-cell analysis.
Cell models (pictured are neurons produced from human embryonic stem cells) allow studying how changes in the genes affect the shape and function of the cell.
News

Cell Bank Reveals Autism's Genetic Roots

Researchers have created 63 genetically engineered mouse stem cell lines to study autism-related mutations, especially copy number variations (CNVs). The library reveals shared protein production issues across different autism mutations.
A close-up photograph of three brown beer bottlenecks.
News

Scientists Identify Neurons Responsible for Suppressing Binge Drinking

Scientists have identified the discrete group of co-activated neurons in the brain that work to suppress binge drinking behaviors. This could become a new therapeutic target for alcohol dependency.
A microglial cell sits between other neural cells, providing immune functions in the brain.
News

Researchers Culture Microglia To Recreate the Brain's Immune System

A stem cell platform aims to recreate the brain's immune system using lab-grown human microglia cells, to understand how it functions – and fails – in neurodegenerative disease.
Illustration of scientists working together to discover the workings of the gut microbiome.
News

Rethinking Fecal Transplants for Better Gut Health

New research from the University of Chicago cautions against the widespread use of fecal microbiota transplants due to the long-lasting, unintended health consequences for recipients.
A twelve-well plate filled with cell culture medium, illustrating the growing interest in organoids.
News

Researchers Grow Heart and Liver Organoids Complete With Blood Vessels

Integrating blood vessels into organoids could allow them to surpass current size limits while making them more useful as biological models.
Villi and microbes in the gut. Nerve cells have been found connected to the villi.
News

Mapping the "Brain in the Gut" Brings Insights to Gastrointestinal Disorders

Researchers have identified three types of nerve cells connected to intestinal villi, suggesting that previously unknown neural networks regulate fluid balance in the gut.
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