Single-Cell Analysis – News and Features

Researchers have found that DNA sequences originating from ancient viral infections can play a critical role in helping cancer to survive and thrive. The researchers suggest that silencing these sequences could help to improve cancer treatments.

Investigators have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering new insight that can potentially help improve the effectiveness of cancer immunotherapy.

KRAS inhibitors are showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment. Now, researchers have discovered a new mechanism of resistance that suggests an opportunity to make the treatment more effective.

Columbia researchers have found that Lgr5+ cells descend from the gut’s true stem cells. This case of mistaken identity may explain why regenerative medicine has not lived up to its promise.

Using single-cell sequencing technology, researchers provide the most comprehensive timeline to date of how the body responds to SARS-CoV-2 exposure.

Two Buck scientists led a team that has revealed for the first time how the lack of gravity affects the cells of the immune system at single cell resolution.

The health of fetal macrophages in the placenta can act as an indicator of the health of fetal brain cells, reveals a new study.

A new study from researchers at Uppsala University establishes that macrophage in the adult ischemic muscle induce a phenotype switch into mural cells to support restoration of functional blood flow and thereby promote healing.

Two independent studies by Columbia scientists suggest that research into the gut’s stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.

The advent of single-cell analysis has marked a transformative era in the life sciences, particularly in the field of drug development. To delve deeper into the subject, Technology Networks spoke with Dr. Nora Fekete-Drimusz, head of biology at ARRALYZE. We discuss the transformative impact of single-cell analysis on life science research and explore how ARRALYZE's multifunctional single-cell platform can support those working in this area.