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Synthetic Biology – News and Features

DNA double helix unravelling.

Synthetic DNA Advances Will Catalyze the Next Wave of Biotherapeutic Innovation

This article explores how biopharmaceutical organizations seeking to remain competitive must adopt innovations, like cell-free long DNA synthesis, to unleash the potential of synthetic biology and accelerate therapeutic development across all facets of genetic medicine.

A side-by-side comparison of cells supported by the oxygenation device (left) and cells without the device support (right).

A Breath of Fresh Air Is Key for Cell-Based Therapies

In 2021, a University-led research team received a contract worth up to $33 million to develop an implantable “living pharmacy” to control the human body’s sleep/wake cycles. Now, the researchers have completed a major step toward achieving this.
A synthetic strain of yeast.

Half-Synthetic Yeast Engineered for the First Time

The Synthetic Yeast Genome Project 2.0 declares a major milestone: it has created a yeast strain comprising over 50% synthetic DNA.
Human hand holding a digital globe representing connectivity and digitization.
Industry Insight

Exploring Key Challenges in Life Science R&D

Technology Networks spoke to Dr. Markus Gershater to learn more about Synthace's Lab automation & experimentation in life science R&D 2023-2024 report, its findings and their significance.
A recycling bin with the triangle recycling logo on the front.

Plastic-Eating Bacteria Turn Waste Into Useful Materials

Researchers have engineered a strain of E. coli that can digest polyethylene terephthalate (PET) plastics and transform them into adipic acid – a useful feedstock for nylon materials, drugs and fragrances.
A body of water.

How an Unexpected Discovery in a University Pond Changed the DNA Rulebook

A recent discovery, published in PLoS Genetics, challenges the “rulebook” of DNA. We speak with the first author, Dr. Jamie McGowan, to learn about the accidental finding and what it means for synthetic biology.
Images created using DNA.

Digitally Creating 16 Million Colors Using DNA

The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. Researchers succeeded in creating fluorescent duplexes that can generate any of 16 million colors.
A scientist holding a thale cress plant.

Plant Chloroplasts Show Potential in Treating Huntington’s Disease

A chloroplast enzyme safeguards plants against pathological protein aggregation that causes Huntington’s and other neurodegenerative diseases. Researchers may have found a way to “copy” the mechanism for application in human cells.
A depiction of the genome.

Synthetic Biology Tool Comprehensively Reveals Gene Regulatory Networks

Pooled promoter responses to TF perturbation sequencing (PPTP-seq) is a new technique that integrates CRISPR gene editing with a combinatorial library containing every known transcription factor in the target genome and corresponding promoters.
Bacterial cells under a microscope.

New Study Uncovers How Bacterial Cells Organize Themselves Before Division

Bacteria live in nearly every habitat on earth including within soil, water, acidic hot springs and even within our own guts. But scientists don’t understand a fundamental process within bacterial cells: how they organize themselves before division.