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The Immune System – News and Features

A 3D model of a human kidney.

Lab-Made Kidneys Grown With Blood Vessels for the First Time

For the first time scientists managed to generate kidney organoids with a complex vascular system. These are asembloids, micrometric organoids formed by the union of kidney organoids with vascular organoids in 3D.
Microscopic view of muscle fibers.

Lab-Grown Muscles Mimic Rare Disease

Biomedical engineers at Duke University have developed a new technique to better understand and test treatments for a group of extremely rare muscle disorders called dysferlinopathy or limb girdle muscular dystrophies 2B (LGMD2B).
A close up of a patients hand hooked to a drip.

Approved Immunosuppressive Boosts the Effectiveness of Existing Checkpoint Inhibitor Therapies

Scripps Research scientists found that a “one-two punch” of combining the immunosuppressive drug ruxolitinib with existing checkpoint inhibitor therapies may be a more effective way to fight some cancers, including Hodgkin lymphoma.
Cells with pink centers and transparent exteriors against a blue background.

Targeting Senescent Cells With Rejuvenation Therapies Could Be Detrimental

Targeting senescent cells with rejuvenation therapies may be detrimental, as these cells play key roles in normal physiology.
Three bottles of milk on a doorstep.

A Microbe and Prebiotic Concoction Stifles Allergic Reactions to Milk

Combining a microbe and a prebiotic encourages the production of an important metabolite for gut health, stifling allergic responses to cow's milk, reveals new study.
A doctor writing on a clipboard.

Enzyme-Based Treatment Improves Lupus Outcomes in Animal Models

An enzyme-based treatment developed by Yale researchers mitigated autoimmunity and reduced death rates in both genetic and non-genetic mouse lupus models, a new study reveals.
A thin electronic sensor on a gloved finger.

New “Smart Bandages” Have Potential to Revolutionize the Treatment of Chronic Wounds

"Smart bandages" that can automatically sense and respond to changes in a wound could revolutionize chronic wound treatment, including diabetic ulcers and surgical wounds.
Gut bacteria.

Gut Health Predicts Serious Infections

The composition of the intestinal flora can predict the chances of developing serious infections such as pneumonia. Researchers from Amsterdam UMC and the University of Turku, Finland, followed more than 10,000 people for 6 years.
Toy letters spelling out autism

People With Autism Are Missing Key Microbial Protectors

Missing microbes that protect the gut may promote behaviors reminiscent of the social impairments associated with autism. Replacing these microbes could alleviate gastrointestinal symptoms and the behavioral changes they provoke.
A woman wearing a mask receives a band-aid after a vaccine.

Cancer Patients Develop Fewer Protective Antibodies to COVID-19

Cancer patients develop fewer protective antibodies to SARS-CoV-2 than the general population, especially after a single vaccine dose, reports a new study.