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Vaccine Design and Testing – News and Features

A vaccine vial.

Symptoms Following a COVID-19 Vaccination Indicate a Supercharged Immune Response

A new study, led by UC San Francisco, has found that COVID vaccine side effects symptoms indicate a robust immune response that is likely to lessen the chances of infection.
A healthcare provider placing a bandage on the injection site of a child who had just received a vaccination

Could a “Tailored” Vaccine Be the Key to Treating Eczema in Children

Researchers have uncovered important immune signatures in children with infected flares of eczema. Technology Networks spoke to Dr. Rachel McLoughlin to learn how these findings could guide the development of a tailored eczema vaccine.
A baby's hand held in an adult's.

No Increased Risk of Preterm Birth Following COVID-19 Vaccine

A new study adds evidence supporting the safety of COVID-19 vaccination during pregnancy, finding that vaccination is not associated with an increased risk of preterm birth.
A vaccine needle going into a vial.

Novel Vaccine Approach Induces Improved Protective Immunity Against COVID-19

A scientific team has engineered a COVID-19 vaccine that induced – in pre-clinical models – very long-lasting, protective immunity against SARS-CoV-2 virus with a single-shot immunisation.
Transmission electron micrograph of HIV-1 virus particles (pink/tan) budding and replicating from a segment of a chronically infected H9 cell (teal).

Novel Vaccine Strategy Promotes Immune Response for Diverse HIV Broadly Neutralizing Antibodies

Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals’ immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs).
Black, white and brown cows with tags in their ears stand in a field.

Diverse Vaccines Crucial for Preparing for a Potential Bird Flu Pandemic

Vaccination remains the most effective strategy for avian influenza prevention and control in humans, despite varying vaccine efficacy across strains.
B cells segregating specific antibodies to mark and subsequently destroy a virus

Metabolic Inhibition Offers a New Approach To Combat Epstein-Barr Virus

Inhibiting a specific metabolic pathway in EBV-infected B cells can diminish infection and reduce the risk of downstream disease. A class of “failed” inhibitor drugs may now receive a second chance in applications aimed at dampening EBV infection.
Chickens in the grass.

Experimental mRNA Vaccine Could Limit the Impact of Avian Flu Outbreaks

An experimental mRNA vaccine against avian influenza virus H5N1 is highly effective in preventing severe illness and death in preclinical models.
Photograph of a vaccine vial with a needle drawing liquid

HIV Vaccine Candidate Induces Broadly Neutralizing Antibodies in Humans

A trial HIV vaccine has triggered low levels of HIV bnAbs in humans. The findings provide proof that a vaccine can elicit bnAbs to fight diverse strains of HIV and that it can initiate the process within weeks after just two immunizations.
A healthcare worker wearing a visor and mask prepares a vaccine.

COVID-19 Re-Vaccinations Elicit Neutralizing Antibodies Against Future Variants

Re-vaccination against SARS-CoV-2 promotes the development of broadly inhibitory antibodies against a wide range of variants, which supports the use of yearly booster vaccines.