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Latest Videos

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Development of a Point-of-Care Diagnostic for Influenza Detection with Antiviral Treatment Effectiveness Indication

The ability to rapidly determine if a patient has an infectious disease and what type of treatment the infection will respond to, would significantly reduce the treatment decision time, shorten the impact of symptoms, and minimize transfer to others.
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Drug Sensitivity and Resistance Testing Platform for Personalized Medicine at the Institute for Molecular Medicine Finland (FIMM)

The High Throughput Biomedicine unit at FIMM Technology Centre provides a wide range of biomedical high throughput assays.
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Oncology Biomarker Testing Current US Practice Baseline and Emerging Trends

This presentation will outline key issues in oncology biomarker testing and describe findings from a study of practices used by National Cancer Institute (NCI) designated cancer centers, the leading U.S. oncology institutions, for testing key biomarkers in three solid tumors - breast, gastroesophageal and non-small cell lung cancers.
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Interfering Peptides Targeting Protein-Protein Interactions

Katja Arndt, University of Potsdam, speaking at Discovery Chemistry Congress 2015.
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Highly-integrated Lab-on-a-chip System for Multiparameter Analysis at the Point-of-care

A lab-on-a-chip system called the "Fraunhofer ivD-platform" has been established which opens up the possibility for an on-site analysis at low costs.
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Imaging Biomarkers - Future or Reality

Imaging has been at the heart of Medicine for many decades. However, its influence is changing as the need increases not only for diagnosis of disease, but also for quantification of disease extent, identification of suitable candidates for treatment and for testing of both treatment response or assessment of potential side effects for new treatments.
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Discovery of Potent and Selective Inhibitors of Monopolar Spindle 1 (MPS1) Kinase

This talk presents the discovery and optimization of potent and selective MPS1 inhibitors based on the 1H-pyrrolo[3,2-c]pyridine scaffold, guided by structure-based design and cellular characterization of MPS1 inhibition.
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New Metabolomics Biomarker for Heart Failure

Metabolomics has been successfully applied to identify and validate biomarkers for congestive heart failure. Diagnosis and risk stratification of heart failure (HF) is challenging.
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Exploring Protein-protein Interactions Using Scaffolded and Assembled Peptides as Synthetic Binding Site Mimics

Jutta Eichler, University of Erlangen-Nuremberg, speaking at Discovery Chemistry Congress 2015.
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Choosing & Using Fragments in the Generation of Selective Kinase Inhibitors

There is often a debate about just how useful fragments are for well-established conventional targets such as protein kinases. Fragment screening however can be extremely valuable, providing critical ideas that lead to novelty, demonstrating how to achieve selectivity, helping dissect and make the most of HTS and literature compounds, alongside maximising ligand efficiency.
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