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Exploring Multiple Dimensions in the Forensics of “Space Candy” With Boston Uni. - Behind the Science

In forensic toxicology laboratories, the accuracy and precision of an analytical technique are essential in determining what drugs or chemicals may have played a role in an individual's death. In #BehindtheScience, Jen travels to Boston University's outdoor research facility, where grad students and law enforcement are trained on crime scene investigation. Is it possible to use one analytical technique to test a variety of different matrices - liquid or solid?

Sabra Botch-Jones, an assistant professor at Boston University School of Medicine's Biomedical Forensic Sciences department, joins Claude Mallet of Waters in the analytical laboratory. They show Jen a protocol to tests solid samples, starting with homogenization to convert the solid into a liquid, followed by extraction, then analysis by multidimensional chromatography, or 2DLC, to identify what drugs to target for analysis.


See their full scientific method in our application note: http://www.waters.com/2Danalysis


Watch our first episode with Sabra and Claude on how forensic laboratories use 2DLC, or LCxLC. https://www.youtube.com/watch?v=CSpzw...


See 2D LC instrument from Waters: http://www.waters.com/waters/ACQUITY-...