Latest Upcoming Webinars & Online Events

An integrated evaluation of the pharmacodynamic and pharmacokinetic properties of a drug is essential for successful translation to the clinic. However, cost-effective methods to measure these parameters at the systems level in pre-clinical models are lacking. Here, we introduce a timsTOF and MALDI-2 workflow to evaluate therapeutic activity. The platform combines ion mobility, mass spectrometry-based imaging, absolute drug quantitation across different biological matrices, in vivo isotope tracing, and global metabolome analysis in the adult zebrafish.

In this webinar, we present a standardized workflow solution, including easy and automated nuclei extraction and isolation for reproducible single-nucleus sequencing analysis.

This presentation will highlight our recent progress in the discovery of N-glycans and phospholipids that significantly contribute to aberrant cancer metabolic pathways in primary tumors and metastases. We have also developed novel MALDI imaging approaches of drugs and drug metabolites that exploit key metabolic differences in tumors.

This inaugural online symposium will explore the tools and techniques being used to study diseases in the lab. Focus will be given to cell culture, organ-on-a-chip and organoid models, as well as, how innovations are enabling researchers to elucidate the underlying biological mechanisms of disease and support diagnostic and therapeutic development.

Join us for an invigorating spatial discussion, where we show the latest data using the PhenoCycler™-Fusion system, the fastest single-cell spatial biology solution.

The novel fragmentation technique, electron activated dissociation (EAD) of the ZenoTOF 7600 system (SCIEX), was employed for peptide mapping of a multispecific monoclonal antibody (mAb) as well as IgG1 and IgG4 mAb samples. A specific focus was put on assessing challenging PTMs, such as glycosylations, amino acid isomers and the localization of a sulfation on a singly charged peptide.