Biomonitoring of toxicants like pesticides and PFAS in humans is essential for understanding how chemical exposure affects our health, yet chemical coverage is currently limited with targeted LC-MS approaches.

Recent technological progress has allowed biologists to measure an unprecedented number of these molecules throughout an organism, providing unique insights into the physiological and pathological conditions of cells and organs, including the aging

Join our free webinar to explore advanced glycan analysis using CE-MS and icIEF-MS. Learn rapid screening, in-depth characterization and strategies for ensuring lot-to-lot consistency in glycosylation profiles during protein therapeutics development.

Mass spectrometry (MS)-based omics technologies have revolutionized our understanding of molecular changes in organisms and are crucial for studying metabolism and related diseases through lipidomics and metabolomics. Despite significant advances, there is still a need for robust analytical methodologies in data acquisition, data processing and annotation.
This webinar will demonstrate how LC-Zeno SWATH DIA outperforms conventional DDA in annotating metabolites and lipids in the model organism Gammarus fossarum. Additionally, the presentation will showcase the effectiveness of electron activated dissociation (EAD) in characterizing lipid species and elucidating metabolite isomers. Finally, the webinar will illustrate how EAD and high-resolution targeted approaches improve structural elucidation and molecular network construction.

As proteomics platforms have advanced, the number of proteins measured and sample throughput have dramatically increased. However, have sacrifices or trade-offs been necessary to make these gains?

The liver is a very good example of how tissue architecture can influence aging. Composed mainly of hepatocytes, the position of these cells is key to their role and determines changes in their metabolism and aging profile.

Researchers from the Max Planck Institute have conducted an in-depth multiomics analysis of functional and healthy hepatocytes, characterizing transcriptional, epigenetic, lipidomic and functional signatures to understand the effects of aging.

In this webinar, you’ll hear all about their research, including the novel perfusion technology for resected mouse liver that makes it easy and convenient to obtain viable hepatocytes to analyze.