Mass Spectrometry: From Imaging to Metabolic Networks

Poster

We show that network analysis of co-localized ions from mass spectrometry imaging data provides a detailed chemo-spatial insight into the metabolic heterogeneity of tumor. Furthermore, module preservation analysis between colorectal cancer patients with and without metastatic recurrence suggests hypotheses on the nature of the different local metabolic pathways.

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Your Brain on Video Games

Video

How do fast-paced video games affect the brain? Prof Daphne Bavelier explains

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Identifying Non-Intentionally Added Substances (NIAS) in Food Contact Materials

Poster

Concern about the safety of food products has increased dramatically with intentionally and non-intentionally added substances (NIAS) used in packaging being of particular interest. APGC and high resolution MS together with a workflow driven process was used to identify unknown compounds in packaging.

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Will Microfluidic Cell Culture Fulfill its Long-awaited Potential?

Article

The first paper ever published on microfluidic cell culture is 19 years old. Microfluidic cell culture has now outgrown its infancy and is about to survive its teenage years. It has matured considerably but still needs to transition from academia into clinics and industry. Will it come of age?

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Making Fragrant Fumes

Making Fragrant Fumes

News

Waste oil from orange, tea tree and eucalyptus essential oil production mixed with diesel provides a sweet-smelling biofuel blend with comparable performance to diesel-only fuel.

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Protein Turnover Rates Differ Across the Brain
News

Scientists have revealed that protein molecules in the brain are broken down and replaced at different rates, depending on where in the brain they are.

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Glial-Neuronal Interaction Fundamental for Memory
News

When astrocytes in mice overproduce a protein called ephrin-B1, the ability of the animal to retain memory weakens.

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Handedness Affects Happiness in Mental Health Treatment
News

Radical new model of emotion in the brain suggests current treatment for the most common mental health problems could be ineffective or even detrimental to about 50 percent of the population.

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Exploiting the Glycome for Cancer Therapeutics

Exploiting the Glycome for Cancer Therapeutics

Article

The surfaces of cancer cells frequently express different types of glycoproteins, and because healthy cells don’t express these molecules (or do so at a much lower level), there has been significant interest in them as potential anticancer targets. Recent advances suggest we are about to see a resurgence in cancer glycomics.

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Food Safety Warnings Are Making Eating More Dangerous
Article

Food hazard warnings are making eating more dangerous

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Scientists Explore the Molecular Mechanics that Drive us to Sleep
Article

Scientists describe how phosphorylation of 80 synaptic proteins drives our sleep/wake cycles

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Cisplatin Efficacy: The Importance of Measuring Uptake in Cancer Cells
Article

Although cisplatin is clinically proven to combat numerous human cancers – bladder, head and neck, lung, ovarian, testicular – resistance to treatment remains a key challenge, and cisplatin patients can often relapse. Having the ability to determine the cellular uptake of cisplatin is key to developing novel strategies to increase tumor cell sensitivity to cisplatin.

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