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Can High-Throughput Technologies Improve Reproducibility in Neuroscience?

Article

By improving sensitivity in quality control, increasing capacity and throughput, and by improving assay development and measurement, high-throughput technologies are helping to overcome the reproducibility crisis in science.

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Developing Stem Cell Therapy Solutions for Liver Disease

Blog

We spoke with Eric Schuur, President and CEO of HepaTx, to learn how the company hopes to develop regenerative medicine solutions for people with liver disease. Eric provides an overview of the steps involved in hepatocyte production and provides insights on the hurdles that need to be overcome, to get these stem cells from the lab to the clinic.

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HIV Protease Movie HiRes

Video

The 3D structure of HIV Protease by Dr. Warren L. DeLano in high resolution.

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A Faster Way to Quantitatively Profile the Lipidome

Article

The lipidome refers to the totality of lipids in cells. In this article, PREMIER Biosoft's Sanjib Meitei explains how his team developed a new technique that can quantitate and separate lipidome sammples in just 15 minutes.

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How 2D-LC is used in forensic science at Boston U. Medical School | Behind the Science, S3 Ep2

Video

Our Behind the Science host Jen goes back to our new 2D-LC lab to meet Claude Mallet, Ph.D., a senior scientist at Waters, and Sabra Botch-Jones, M.S., M.A., D-ABFT-FT, an assistant professor in the department of Anatomy & Neurobiology, Biomedical Forensic Sciences, at Boston University School of Medicine (http://www.bumc.bu.edu/gms/msci/about...) to learn how her lab uses 2DLC.

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Crisis That'll have Us Crying into What's Left of our Beer

Crisis That'll have Us Crying into What's Left of our Beer

News

Scientists project that human-caused climate change will result in one of the most dire consequences imaginable: a disruption in the global beer supply.

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Cesarean-Born Mice Show Altered Patterns Of Brain Development
News

The team of neuroscientists examined the effect of birth mode (vaginal delivery versus Cesarean section) on neuronal cell death, an important process that reshapes neural circuits early in development.

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Scientists Chase Mystery of How Dogs Process Words
News

“Many dog owners think that their dogs know what some words mean, but there really isn’t much scientific evidence to support that.”

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Does the Brain Really Feel no Pain?

Does the Brain Really Feel no Pain?

Article

The brain has no nociceptors – the nerves that detect damage or threat of damage to our body and signal this to the spinal cord and brain. This has led to the belief that the brain feels no pain. A belief that has entered popular culture.

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Exploring the Public’s Perception of Food Fraud
Article

When you go to the shops to buy the weekly groceries, it’s quite likely you’ll find yourself thinking about where your food has come from. Is this organic? Is that free-range? You are perhaps less likely to find yourself wondering, “Is this food fake?”

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Healthcare Interoperability Woes: Three Solutions that Create Optimism
Article

Healthcare interoperability remains an intractable problem; both healthcare providers and patients feel unease about limited access to medical data, which results in lower care quality and poor patient engagement. Although daunting, these challenges aren’t insurmountable. In this feature, we’ll explore what has been and what could be done to foster the creation of an interoperable infrastructure.

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Understanding the Lytic Cycle – What Are the Steps?
Article

Bacteriophage (phage) are viruses that specifically infect bacteria. They have a two-phase lifecycle, residing in a dormant state within the host genome (lysogenic cycle) or hijacking the host cellular machinery for their own replication (lytic cycle). Here we will explore the important steps of the lytic cycle.

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