Application Notes

 
A Monolayer Culture Method for Neural Induction of hPSCs
Application Note

Method for neural induction using STEMdiff™ Neural Induction Medium in a monolayer culture system.

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Neuronal Differentiation of hPSC-Derived Neural Progenitor Cells
Application Note

Culture in BrainPhys™ Neuronal Medium results in cultures that are phenotypically mature and, after 65 days in culture, synaptically active.

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Detection of RNA in the central and peripheral nervous system using the RNAscope® in situ hybridization assay
Application Note

The RNAscope® in situ hybridization (ISH) assay provides a powerful method to detect gene expression within the spatial and morphological tissue context.

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Image-Based Analysis of a Human Neurosphere Stem Cell Model for the Evaluation of Potential Neurotoxicants
Application Note

Here we demonstrate a 3D neurosphere model, composed of hNSCs, to conduct toxicity testing of several potential neurotoxicants.

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Nanobubble Applications and Characterization by Nanoparticle Tracking Analysis
Application Note

The generation, measurement, and applied technologies of so-called nanobubbles or ultra-fine bubbles, with diameter ranging from tens to hundreds of nanometers, are evolving dramatically in recent years.

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How Investing in Malvern Instruments Helped KBI Biopharma Find a Clear Commercial Advantage
Application Note

As our understanding and awareness of the importance and impact of particles in drug products increases, their characterization becomes ever more necessary, both from a perspective of ensuring drug stability, safety and efficacy, and also from the standpoint of meeting regulatory expectations.

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Gold Nanoparticle Applications and Characterization by Nanoparticle Tracking Analysis
Application Note

Gold nanoparticles are one of the most popular and extensively researched type of nanoparticle.

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Analysis of Trace Elements in Water by EPA 200.8 Analyses
Application Note

Shimadzu

This application note describes the methodology and use of the Shimadzu ICPMS-2030 ICP mass spectrometer for the analysis of trace elements in drinking and fresh waters following the EPA 200.8 method.

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Analysis of Orthophosphate, Nitrate Nitrogen, and Hexavalent Chromium in Water Samples
Application Note

Shimadzu

In this document, Shimadzu reports the use of their benchtop UV-1280 UV-Vis spectrophotometer for the analysis of three water contaminants – phosphate, nitrate, and hexavalent chromium.

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Investigating the Effects of Excipients on the Earliest Stages of Aggregation - Aggregation Inhibition by Arginine
Application Note

Malvern Instruments Limited

Use of static and dynamic light scattering to characterize the stability of lysozyme in the presence and absence of arginine. SLS is used to assess aggregation temperature, while DLS is used to measure the various particle sizes present in the two formulations at different temperatures, and measurements of zeta potential are used to assess the effect of arginine on the charge state of the protein.

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