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Latest Application Notes
Mannose Glycans Content Screening for Human-mAb Samples
Application Note

Mannose Glycans Content Screening for Human-mAb Samples

Glycosylation refers to the formation of linkages with glycosyl groups, covalently attaching a carbohydrate to another molecule. Antibody glycosylation is critical due to the role carbohydrates play in modulating effector functions which affect safety and efficacy of therapeutic antibodies.
Versatile Fragment Analysis for Your Workflow Needs
Application Note

Versatile Fragment Analysis for Your Workflow Needs

Fragment analysis of nucleic acids is an essential, well-known molecular biology tool used in many different research areas. Applications such as cloning, gene editing and fragment length analysis rely on quality control checks to assess the nucleic acid size at the beginning or middle of the workflow to ensure successful end results.
Successful and Stress-Free LC Method Transfers
Application Note

Successful and Stress-Free LC Method Transfers

As LC methods are moved from the “transferring” to the “receiving” system, scientists are required to navigate multiple variables resulting from instrument settings or vendor configuration that directly impede method transferability.
Transforming Drug Discovery Through Precision Research
Application Note

Transforming Drug Discovery Through Precision Research

The high resolution and scale that single cell analysis provides is revolutionizing drug discovery and development by introducing comparative, longitudinal and causal information that transforms our ability to understand biology and disease.
Identification of a Tumor–Specific Gene Regulatory Network in Human B-Cell Lymphoma
Application Note

Identification of a Tumor–Specific Gene Regulatory Network in Human B-Cell Lymphoma

Download this app note to discover how to distinguish tumor versus normal cells in a heterogeneous sample, reconstruct cell type–specific gene regulatory network
and confirm PAX5 as a critical regulator specific to tumor B cells.
Lab Ultrafiltration - Tips and Tricks
Application Note

Lab Ultrafiltration - Tips and Tricks

Download this compendium to discover tips and tricks for ultrafiltration including how to desalt samples, concentrate samples and recover low-concentrated samples.
Imaging Organoids With Light-Sheet Fluorescence Microscopy
Application Note

Imaging Organoids With Light-Sheet Fluorescence Microscopy

Studying tissue and organ biology is challenging, particularly in mammals, given sample accessibility and ethical concerns. However, the use of organoids alleviates these challenges, supporting researchers in exploring questions that previously could not have been investigated without them.
Accurate Quantification of Interferon Gamma Across Immunoassay Platforms
Application Note

Accurate Quantification of Interferon Gamma Across Immunoassay Platforms

Download this app note to discover immunoassay platforms that are consistent for your cell therapy and immunology development needs.
Organoids for Disease Modeling and <i>In Vitro</i> Drug Screening
Application Note

Organoids for Disease Modeling and In Vitro Drug Screening

While the complexity of organoids remains challenging, technological advances are enabling organoids to be developed and monitored in an automated fashion, so that they can be exploited in high-throughput drug screening assays.
3D Co-Culture Spheroids With Human Liver Cells
Application Note

3D Co-Culture Spheroids With Human Liver Cells

With the advances in 3D culture, liver spheroids made from primary human hepatocytes have been demonstrated to be a useful novel tool for in vitro hepatotoxicity studies.
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