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Latest Application Notes

Application Note

Quick and Easy Solution for Plasmid Analysis

Because of this, plasmids ideally suit experimental protocols that include cloning. Inserting a piece of DNA into the linearized plasmid and generating multiple copies of the plasmid allows scientists to study DNA sequences or genes.
Application Note

Gene Modification for Cell Therapy Applications

The clinical success of CAR T-cell therapy has spurred increased interest and investments in the advanced therapeutics industry.
Application Note

Detection and Characterization of Mitochondrial Toxicity

A Customized XF Workflow for Detection and Characterization of Mitochondrial Toxicity

Many different classes of drugs can cause drug-induced mitochondrial toxicity, which may result in brain, cardiac, liver, muscle and/or kidney injury.
Application Note

Benefits of Quality Control in the IVT RNA Workflow

The importance of quality control (QC) in laboratory processes is often overlooked but should be considered an essential part of every procedure.
Application Note

Kinetic Curvature: Assessment of Small Molecule Kinetics and Affinity

Surface plasmon resonance (SPR) is a core technology used in many pharma and biotechnology settings for this purpose, however traditional initial SPR screening of weak affinity compounds using a single fixed concentration injection can present numerous challenges.
Application Note

CRISPR Engineered Cells Enable Variant Disease Modeling

Comprehensive disease modeling can be challenging for many labs due to variations in reagents, cell culture conditions, technical inconsistencies across protocols and experiments and bandwidth limitations.
Application Note

Analytical Method for Pesticide Residue in Cannabis Flower

Since there are no federal regulations for pesticide analysis in cannabis, individual states have developed their own regulations outlining the list of pesticides to monitor and the maximum residue limits or acceptable limits for each pesticide.
Application Note

Run and Done Isobaric Quantitation With PaSER

Mass spectrometry-based proteomics provides wide depth and quantitation. But how do we quickly and effectively analyze the data produced?
Application Note

Development of a Targeted Plasma Quantitation Assay Using dia-PASEF

In clinical proteomics research applications, blood plasma is the key sample of interest, but comprehensive proteome analysis can be challenging due to the large dynamic range of concentration.
Application Note

Progress Towards Out-of-the-Box Sub-Cellular Imaging

Single cell analysis in a spatially resolved context is the gateway to deciphering scientific questions in various application areas. Such analysis requires the highest available spatial precision combined with highly sensitive detection.
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