Latest App Notes & Case Studies
App Note / Case Study
Rapid Phosphoproteomics With DIA-PASEF
Data-independent acquisition (DIA) has been shown to increase the quantitative reproducibility and accuracy of MS-based phosphoproteomics. This app note explores the impact of dia-PASEF on the speed and sensitivity of phosphoproteomics.
App Note / Case Study
A Novel Method To Assess Sequence Integrity for RNA Therapeutics
RNA-based therapies can modulate cells in a controlled and targeted manner, effectively acting as gene therapies. But, as with any therapeutic, RNA therapeutics must undergo strict quality control (QC) to ensure the product is exactly as specified, with no errors or alternate products.
App Note / Case Study
Superior Characterization of Biotherapeutic Quality Attributes Using Electron Activated Dissociation
The multi-attribute method (MAM) is a powerful LC-MS method that overcomes this challenge by simultaneously monitoring and quantifying multiple PQAs in a single injection.
App Note / Case Study
Simple and Fast Tracking of Drug–Antibody Ratio Distribution
Antibody drug conjugates (ADCs) are biotherapeutics, composed of small molecule drugs conjugated to an antibody scaffold, that have very complex molecular structures.
App Note / Case Study
Advanced Flow Cytometry for Cell Line Development
Traditional methods are often low throughput, time-consuming and lack linearity. However, advanced flow cytometry has emerged as a more efficient alternative for biologics development.
App Note / Case Study
Maximize Your Long-Read Sequencing Results
Routine, robust methods for long-read sequencing have the potential to allow researchers to analyze long stretches of DNA without the requirement of preamplification and can also enable analysis of complex regions that are otherwise difficult to map.
App Note / Case Study
Automated Parallel Capillary Electrophoresis for Purity Analysis of ssDNA and RNA Oligonucleotides
As oligonucleotides (oligos) are synthesized, small amounts of impurities can be introduced at each step, and different synthesis methods and purification efficiencies can impact the quality of the sample.
App Note / Case Study
An Integrated Multiomic Approach for the Diagnosis of Metabolic Diseases
Inherited metabolic disorders (IMDs) are a vast and complex group of rare genetic diseases presenting throughout a patient’s life span.
App Note / Case Study
A Fully Integrated Spatial Biology Analysis Solution
Extracting biological insights from spatial data is vital to advancing science, however, the analysis of spatial multiomics data is only possible with a robust and scalable informatics solution.
App Note / Case Study
Improving qPCR Reliability With Automated RNA Normalization and Plate Setup
Quantitative real time PCR, often coupled with reverse transcription (RT-qPCR), is a powerful technique for detecting differences in the copy number of nucleic acids and can be used for analysis of gene expression.
Advertisement