Latest App Notes & Case Studies

The scale of research into potential gene therapies often means that work is distributed across multiple locations. Investigators must have confidence that the results obtained at one site are consistent with results obtained at other sites participating in the study.

This app note presents a robust workflow that combines automated sample preparation, hydrophilic interaction chromatography and triple quadrupole mass spectrometry that can be applied to plasma and mammalian cell samples.

Serological pipettes are commonly used in cell culture applications when pipetting volumes greater than 1,000 µL. However, their plastic (disposable) nature, coupled with the inability to pre-set the volume and propensity to cause shoulder strain, are just some of the limitations faced by researchers in the lab.

The miniaturization of FTIR into a handheld, portable solutions, now offers a more rapid analysis of photovoltaic cells than ever before

Single-cell RNA sequencing produces a substantial amount of complex data that can be a burden if you don’t have time to become an expert in bioinformatics.

Spatial biology requires highly validated reagents to accurately resolve proteins in the tissue microenvironment. Although immunofluorescence techniques are some of the most commonly used research tools, there are no universally accepted guidelines for antibody validation.

This application focus summarizes the key points from a webinar focused on the benefits and applications of automated liquid handling.

Before you can embark on one of the many applications involving genomic DNA (gDNA), it is important to assess the quality of your samples, especially if these samples could have been exposed to physical shearing or enzymatic degradation.

Data-independent acquisition (DIA) has been shown to increase the quantitative reproducibility and accuracy of MS-based phosphoproteomics. This app note explores the impact of dia-PASEF on the speed and sensitivity of phosphoproteomics.

RNA-based therapies can modulate cells in a controlled and targeted manner, effectively acting as gene therapies. But, as with any therapeutic, RNA therapeutics must undergo strict quality control (QC) to ensure the product is exactly as specified, with no errors or alternate products.