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Latest Application Notes

Application Note

LC Triple Quadrupole Clinical Research Compendium

Liquid Chromatography with tandem mass spectrometry (LC-MS-MS) is a powerful analytical technique that combines the separating power of liquid chromatography with the highly sensitive and selective mass analysis capability of triple quadrupole mass spectrometry.
Application Note

Is This Europe’s Most Modern Biobank?

The University of Szeged is one of Hungary’s leading research institutions with a long history of pioneering scientific achievements. For generations, the university’s scholars have been focused on collecting and storing biological samples for educational purposes as well as for clinical, biomedical and physiological research.
Application Note

Accurately Analyze Fluorescent Widefield Images

The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However, out-of-focus fluorescence increases background, reduces contrast and makes accurate image segmentation more challenging.
Application Note

Cold Activation of TRPM8 Using a temperature controlled External Perfusion System and the Port-a-Patch

Download this app note to learn more about how TRPM8 channels have been implicated to play a role in cancer, in particular prostate and pancreatic cancer.
Application Note

How To Choose the Correct Syringe Filter for Analytical Sample Preparation

Download this app note to learn more about how to protect your chromatography columns, achieve optimum performance plus ensure data integrity.
Application Note

How Syringe Filtration With Integrated Prefilter Technology Improves HPLC Performance and Throughput

In many laboratories, the need to consistently generate high -quality data means that managers, scientists and technicians must ensure their instruments are performing optimally around the clock.
Application Note

Resolving Brain Architecture With Comprehensive Spatial Gene Expression

Spatially resolved gene expression can provide a powerful complement to traditional histopathology methods, enabling a greater understanding of cellular heterogeneity and organization within the central nervous system.
Application Note

Separation of Isobaric Androgens Using MALDI-2 TIMS Imaging

In order to develop novel therapeutic treatments, it is key to understand the tissue-specific steroids metabolic pathways. Mass Spectrometry Imaging (MSI) is a powerful tool to visualize the distribution of such molecules involved in tissue metabolism.
Application Note

Digital Asset Management in A Pharmaceutical Laboratory

Research scientists are all too familiar with the catastrophic effects of equipment failure. During October 2020, a pharmaceutical lab associate lost several months’ worth of work due to three incubators losing humidity control resulting in the loss of valuable cell lines.
Application Note

Deep Learning-Based Image Analysis for Label-Free Monitoring of iPSC and 3D Organoid Cultures

Complex 3D biological models such as organoids and patient-derived spheroids are gaining popularity in many biomedical research areas because they more closely recapitulate in vivo tissues.
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