Application Notes

 
Analysis of Orthophosphate, Nitrate Nitrogen, and Hexavalent Chromium in Water Samples
Application Note

Shimadzu

In this document, Shimadzu reports the use of their benchtop UV-1280 UV-Vis spectrophotometer for the analysis of three water contaminants – phosphate, nitrate, and hexavalent chromium.

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Investigating the Effects of Excipients on the Earliest Stages of Aggregation - Aggregation Inhibition by Arginine
Application Note

Malvern Instruments Limited

Use of static and dynamic light scattering to characterize the stability of lysozyme in the presence and absence of arginine. SLS is used to assess aggregation temperature, while DLS is used to measure the various particle sizes present in the two formulations at different temperatures, and measurements of zeta potential are used to assess the effect of arginine on the charge state of the protein.

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Using DSC to Characterize Thermotropic Phase Transitions in Lipid Bilayer Membranes
Application Note

Malvern Instruments Limited

The basics of liposome sample preparation and DSC studies.

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Monitoring Microfiltration Processes for Water Treatment
Application Note

Malvern Instruments Limited

Quantifying nanoparticle concentration and size to optimize filtration processes.

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Particle Size Analysis of Calcium Carbonates by Laser Diffraction
Application Note

Malvern Instruments Limited

Calcium Carbonate is used within a wide range of industrial products as a filler and pigment. It is also used as a source of calcium within food and pharmaceutical products. Its function is often related to its particle size and size distribution.

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Optimization of a Multi-Mode Detection Model for Measuring Real-time Cellular Respiration and Mitochondrial Function using Fluorophoric Biosensors
Application Note

BioTek Instruments Inc.

Cellular metabolism characterization is being aided by the development of new tools designed to provide ease-of-use, higher throughput, and multiplexed data markers for analysis.

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Monitoring Saccharomyces Cerevisiea Growth with Bright Field Microscopy in Real Time
Application Note

BioTek Instruments Inc.

Strains of the yeast Saccharomyces cerevisiea serve critical roles in the production of many different products including food staples, medicines, and biofuels. The ability to obtain the desired product reliably and repeatedly requires careful monitoring of not only the input materials, but the growth of the yeast strain during the process.

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Protein Storage and Stability Analysis Using the Zetasizer Nano ZSP
Application Note

Malvern Instruments Limited

Spidroins are large, structural proteins that make up the bulk of spider silk fibres. This application note describes the use of a Zetasizer Nano ZSP to characterize their stability at different temperatures.

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Preformulation and Stability Studies of Biotherapeutics Using DSC
Application Note

Malvern Instruments Limited

The Malvern MicroCal VP-Capillary DSC has been used for rapid screening of buffers in preformulation development and for the optimization of storage conditions of antibodies during process development. The results correspond well with those obtained by other more time-consuming methods.

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