Latest App Notes & Case Studies

In the past two decades, genotyping arrays have been instrumental in the large-scale characterization of single nucleotide polymorphisms (SNPs) and the genetic makeup of individuals. Targeted sequencing has yet to fully replace microarrays due to barriers associated with performance at scale.

Even in small quantities, many elements can have toxic effects when present in drinking supplies or food chains. As such, monitoring the trace elemental composition of drinking, waste, and surface waters (such as rivers, lakes, and ponds) is vital in the maintenance of human, animal, and environmental health.

To prevent new infections in China once the number of cases fell, all nationals returning from other countries were tested. This process required rapid testing and automation of the sample preparation process. In order to meet these requirements, scientists have exploited automated pipetting solutions. Download this app note to discover tips on how to automate the testing of suspected COVID-19 positive cases.

Download this app note to discover a high-throughput, multiplex assay that can profile large libraries of mAbs for their effects on antibody-dependent cellular phagocytosis in minimal time.

Environmental water screenings are regularly challenged by the number and diversity of chemical and biological targets in each sample. Download this app note to find out the advantages of this environmental screening method.

When COVID-19 arrived very few people had anticipated the impact a pandemic would have on the global population and the life sciences industry. Many laboratories are archiving positive COVID-19 samples for future research. Access this app note to discover the uses and advantages of automated storage.

Because of problems in common PCR-based mutagenesis techniques, there is an urgent need to develop efficient screening and selection tools for biocatalyst improvement. Download this app note to discover a novel approach using solid-phase synthesis of oligonucleotides

Download this app note to discover an example that shows pooling crRNAs to the same gene target provides robust functional knockout and reveal ways to ensure crRNA pools work successfully in phenotypic screening.

Viruses are obligate intracellular pathogens that can infect all living organisms. A clear understanding of host–virus interactions is crucial to uncover the molecular mechanisms underpinning infection and to enable the development of new treatments.

Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, the need for rapid testing and screening has never been more important. Download this app note to discover how Raman spectroscopy can be used for rapid trace-level detection of viruses and antibodies.