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Application Notes

 
Automated Online Card Extraction LC/MS System for the Determination of Clozapine and its Metabolites in Rat Blood
Application Note

Agilent Technologies Inc.

This application note describes the development and validation of a method on the AACE LC/MS system for the online analysis of DBS cards for the quantitation of clozapine and two of its metabolites in rat whole blood.

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Micro-Volume Purity Assessment of Nucleic Acids using A260/A280 Ratio and Spectral Scanning
Application Note

BioTek Instruments Inc.

The spectrophotometric ratio of absorbance measurements at 260 nm and 280 nm provides a rapid indication of protein contamination in nucleic acid isolates and less commonly, nucleic acid contamination in protein isolates. UV-Vis scanning can also identify contamination from chemical additives used in the isolation procedure. This application note assesses the capability in micro-volume analysis using the BioTek Take3™ microplate accessory.

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Recombinase Polymerase Amplification
Application Note

TwistDx

This application note explains the advantages of RPA and how it simplifies the engineering challenges for point-of-care diagnostics.

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Automation of a Generic Fluorescent Methyltransferase Activity Assay
Application Note

BioTek Instruments Inc.

The primary function of this application note is to demonstrate automated methods for a HTS-ready universal methyltransferase activity assay.

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Analyzing Biological Samples
Application Note

This technical note describes the capability of Tecan’s Infinite® 200 PRO multimode reader to regulate the CO2 partial pressure inside its measurement chamber.

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Performance Qualification of an Automated Plate Washer Using the Artel MVS®
Application Note

Artel

The purpose of this application note is to demonstrate the ability of the MVS® Multichannel Verification System to test the performance of an automated plate washer. The previously written application notes, Using the MVS to Measure Residual Volumes Remaining in a Plate After Sample Aspiration: General Approach1 will be cited within as these unique applications relate to this discussion involving tests for (1) bulk dispense precision and accuracy and (2) volume evacuation efficiency.

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Using the MVS to Measure Residual Volumes Remaining in a Plate After Sample Aspiration: General Approach
Application Note

Artel

The purpose of this application note is to demonstrate an alternative use for the Artel MVS® Multichannel Verification System. As opposed to measuring the accuracy and precision for a volume transfer of sample into a microtiter plate, the MVS is instead used to measure resididual liquid after sample is aspirated out of each well.

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Artel MVS as a Tool For Measuring Liquid Mixing Efficacy in Microplates
Application Note

Artel

This application note describes how the ARTEL MVS® Multichannel Verification System can be used as a tool for measuring the efficacy of liquid mixing protocols.

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Rapid Wheat Varietal Identification using the Agilent 2100 Bioanalyzer and Automated Pattern-Matching
Application Note

Agilent Technologies

Accurate identification of wheat varieties is of paramount importance to the milling industry in many countries. This Application Note describes how the Agilent 2100 bioanalyzer and the Protein 230 assay can be used in conjunction with a third-party software, to analyze wheat proteins for varietal identification.

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Evaluation of Forward and Reverse Mode Liquid Handling Techniques Using the ARTEL MVS®
Application Note

Artel

This study illustrates the use of the Artel MVS® Multichannel Verification System to rapidly evaluate the accuracy and precision of dispensed volumes from the Caliper RapidPlate liquid handler.

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