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Latest Application Notes
Studying the Molecular Mechanism of Viral Replication in Real Time
Application Note

Studying the Molecular Mechanism of Viral Replication in Real Time

Download this app note to discover a fluorescent-based approach that can enable real-time measurement of viral gene expression and be used to study virtually any virus in a 96- or 384- well format.
Enhancing the Therapeutic Properties of a Cancer-Targeting Affibody by Soft Mutagenesis
Application Note

Enhancing the Therapeutic Properties of a Cancer-Targeting Affibody by Soft Mutagenesis

Affibodies are synthetic antigen-binding proteins. They offer many advantages over monoclonal antibodies, including smaller sizes, enhanced thermal stability and rapid refolding capability. These advantages make affibodies an attractive platform for the development of therapeutics, diagnostics and bioimaging technology.
Tiling Across Viral Genomes to Investigate Immune Escape
Application Note

Tiling Across Viral Genomes to Investigate Immune Escape

Viruses exploit high-dimensional RNA structures to facilitate viral replication and impede host restriction. Here, a novel next-generation sequencing (NGS)-based screening workflow, called Fate-seq, was used to define and characterize high-dimensional RNA structures.
Discover Triple Quadrupole ICP-MS for the Analysis of Trace Elements
Application Note

Discover Triple Quadrupole ICP-MS for the Analysis of Trace Elements

Triple quadrupole ICP-MS systems allow for consistent interference removal regardless of the sample matrix and provide a significant improvement for detection limits of challenging analytes.
Convenient Customization of Your Cation Exchange Analysis
Application Note

Convenient Customization of Your Cation Exchange Analysis

Therapeutic monoclonal antibodies (mAbs) are highly heterogeneous molecules due to being composed of a large number of variants. When the variants are present in the pharmaceutical protein, it is possible their biological activity could be altered.
Extraction and Recovery of Perfluoroalkyl and Polyfluoroalkyl Substances
Application Note

Extraction and Recovery of Perfluoroalkyl and Polyfluoroalkyl Substances

Polyfluorinated surfactants (PFS) are the main group of chemicals in commercial packaging blends and are a cause of major concern as they can be precursors of poly- and per-fluorinated alkyl substances (PFAS), which have been linked to cancers, decreases in fertility and reduced immune system function.
Benefits of an Ergonomic and Electronic Pipette for RT-PCR
Application Note

Benefits of an Ergonomic and Electronic Pipette for RT-PCR

Pipetting ergonomics has emerged as an important consideration in the research laboratory, especially during the past year when diagnostic laboratories were forced to work for long hours due to the global SARS-CoV-2 pandemic.
Confidence in Your Nitrosamine Impurity Analysis
Application Note

Confidence in Your Nitrosamine Impurity Analysis

After the discovery of unacceptable levels of nitrosamine contaminations in certain drug products, regulatory agencies around the world have mandated stringent guidelines and analytical testing of all pharmaceuticals, especially chemically synthesized ones.
Analysis of Microplastics in Suspended Solids With TG-GC-MS
Application Note

Analysis of Microplastics in Suspended Solids With TG-GC-MS

Download this app note to learn about a technique that can provide greater detail, higher-resolution results and analyze complex sample relationships.
Solutions for Pharmaceutical Impurities
Application Note

Solutions for Pharmaceutical Impurities

With an ever-increasing consumption of pharmaceutical products by the world population, there are considerable concerns about the unknowns and impurities which are ingested along with these medicinal drugs
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