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Latest App Notes & Case Studies

App Note / Case Study

Microbial Detection and Quantification Using the IntelliQube® from Douglas Scientific®

Nucleic Acid Testing (NAT) is a powerful tool for the quantification of microorganisms and are used in many fields. In this study commercially available microbial NAT kits were successfully miniaturized from 20 µL to 1.6 µL reaction volumes using the IntelliQube. The IntelliQube delivers efficient and economical high throughput sample processing for microbial qPCR applications.
App Note / Case Study

Evaluation of a New Accurate, Automated and Cost-effective Approach for the Analysis of Pharmacologically Important Copy Number Variation

The IntelliQube® from Douglas Scientific® is designed to address the need for accurate and reliable results for studies such as CNV determination.
App Note / Case Study

Formation of Monodispersed Microbubbles

This application note describes how the Mitos P-Pump can be used in combination with the Droplet Junction Chip to produce monodispersed gas bubbles.
App Note / Case Study

Gas Bubble Generation in Water using Dolomite's Small Droplet System

This application note describes a hydrodynamic flow-focussing based system for the monodisperse formation of nitrogen bubbles using the Small Quartz Droplet Chip based Small Droplet System.
App Note / Case Study

Quantifying µ-Scale Mixing Time of Sodium Hydroxide and Phenolphthalein Using Dolomite's Micromixer System

This application note evaluates mixing using a rapid chemical reaction causing a colour change as the indicator of mixing.
App Note / Case Study

Introduction to Mixing and Droplet Production in Microfluidics using Dolomite's Educational Microfluidic System

This application note introduces researchers to fundamental fluid operations in microfluidics using Dolomite's Educational Microfluidic System.
App Note / Case Study

Characterisation of Droplet Junction Chip with Hexadecane and Water

This application note describes how Dolomite's Droplet Junction Chip can be used to generate water droplets in a hexadecane oil carrier stream. By controlling the pressure of the oil and water input reservoir, different flow regimes and droplet sizes were observed.
App Note / Case Study

Mitos P-Pump Droplet Monodispersity

The unique pulseless pressure driven pumping technology of the Mitos P-Pump offers the best solution for droplet formation applications providing a coefficient of variation in the droplet diameter of less than 0.6%. A comparison of the size consistency of droplets formed by the Mitos P-Pump and a market leading syringe pump
App Note / Case Study

Parallel Droplet Generation

This application note describes the performance of a reliable and versatile high throughput system which features Dolomite's innovative 6-Junction Droplet Chip with 6 individual flow-focussing junctions and is capable of consistently producing up to 600ml of emulsion over a 24-hour period as well as highly monodispersed droplets ranging from 20µm to 60µm in diameter.
App Note / Case Study

Mitos Dropix Droplet Generation System: Demonstration of Droplet-on-Demand Sequencing

Mitos Dropix technology now introduces liquid sampling and processing over a very wide 10 nL – 50 µL volume range utilizing droplet technology. Droplet-on-demand sequencing and droplet library generation is demonstrated with the Mitos Dropix® Droplet Generation System in this application note.
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