Latest App Notes & Case Studies

This application note describes the performance of a reliable and versatile high throughput system which features Dolomite's innovative 6-Junction Droplet Chip with 6 individual flow-focussing junctions and is capable of consistently producing up to 600ml of emulsion over a 24-hour period as well as highly monodispersed droplets ranging from 20µm to 60µm in diameter.

Mitos Dropix technology now introduces liquid sampling and processing over a very wide 10 nL – 50 µL volume range utilizing droplet technology. Droplet-on-demand sequencing and droplet library generation is demonstrated with the Mitos Dropix® Droplet Generation System in this application note.

The IntelliQube performs at an industry leading level, facilitating outstanding qPCR results with Array Tape® and the added benefits of inline automation. Liquid handling, thermal cycling, and detection systems within the IntelliQube enables users to achieve efficient and economical high throughput sample processing in Array Tape without compromising important parameters of qPCR performance.

Changes in microRNA (miRNA) expression have been shown to be associated with a variety of normal physiological processes, as well as diseases including cancer. Studies have already shown that miRNAs may provide useful markers for the development of disease diagnostic and prognostic assays.

The particle size of the fat droplets present in dairy and other food emulsions is important in defining properties such as flavor release, mouth feel and the emulsion stability.

Chocolate occupies a special place in the Western palate and one of its attractions is known to be due to its unique mouthfeel.

Analysis of data from the 1999-2002 National Health and Nutrition Examination Survey (NHANES)* indicated that an estimated 65 million individuals in the United States have hypertension.

This study demonstrates that the Nexar® with the FlexJet multi-array dispense feature can reduce master mix consumed as dead volume by 87.5% compared to Dispense Jet single-array dispense. The capability to perform multi-array dispense with one aspiration also produces repeatable and accurate results and is an ideal solution for genotyping applications.

This study demonstrates the ability of the IntelliQube along with Array Tape®, to successfully achieve two multiplexed SNP genotyping results in a single well and decrease thermal cycling times without compromising data quality. The combination of achieving two results per reaction well and shortened cycling times dramatically increases overall throughput.

This study evaluated multiplex genotyping on the IntelliQube, a PCR instrument optimized for 1.6 µL reaction volumes in Array Tape®. It demonstrates the feasibility of achieving two SNP genotyping results in a single reaction well. IntelliQube provides cost savings through miniaturized PCR reaction volumes, shorter thermal cycling times, and multiplex reactions without compromising data quality.