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Latest App Notes & Case Studies

App Note / Case Study

Chromatrap® – Targeting the Epigenetic Landscape Alongside Low Abundant Transcription Factor Recruitment

This application note demonstrates the sensitivity, selectivity and reproducibility of solid phase Chromatrap®, as an assay for Chromatin IP from low cell numbers.
App Note / Case Study

Real-time Monitoring of Genetically Encoded Redox Probes in Mammalian Cell Monolayers

In this application note we show that the PHERAstar FS reader enables roGFP2-based measurements in mammalian cell monolayers grown in 96-well imaging plates.
App Note / Case Study

Blood Cell Analysis with the Moxi Z

This application note discusses how Moxi Z can generate important metrics from blood samples for non-clinical analysis including red blood cell (RBC) counts, mean corpuscular volume (MCV), white blood cell (WBC) total counts and peripheral blood mononuclear cell (PBMC) size distributions and counts.
App Note / Case Study

Whole-Mount Slide Imaging in Traumatic Brain Injury Research

This application note describes how the TissueScope™ solution provides researchers with the opportunity to effectively map the entire brain, and link detailed cytoarchitectural maps with functional imaging data.
App Note / Case Study

Ensuring Sectioning Quality in TMA Analysis for the Human Protein Atlas Project

This article describes how the tissue microarrays and slides are made, and how a rotary microtome with different cutting modes and an automated Section Transfer System together ensure that high-quality, reproducible sections are generated.
App Note / Case Study

Sectioning of Bone as a Specialist Histology Specimen

This application note discusses how the Thermo Scientific HM355S and Finesse ME+ Automated Microtomes deliver quality sections from bone tissue.
App Note / Case Study

Proteomic Analysis of Laser Microdissected FFPE Tissue Using Mass Spectrometry

This application note discusses a study which was undertaken to identify candidate protein biomarkers for early detection of endometrial cancer using formalin fixed paraffin embedded tissue samples.
App Note / Case Study

Mass Spec Protein Assays in FFPE Tissue

This application note discusses how the Liquid Tissue®-SRM platform makes possible quantitation of proteins and their phosphorylation states by mass spectrometry using small amounts of laser microdissected FFPE tissue.
App Note / Case Study

Triggering with the Leica TCS SP5, TCS SP5 II and DM6000 CFS

This document provides detailed information about triggering with the Leica TCS SP5, TCS SP5 II and DM6000 CFS systems.
App Note / Case Study

On-screen Analysis: Review Captured Cells on-Screen

This application note shows the methodology for viewing and evaluating captured cells on screen.
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