Latest App Notes & Case Studies
App Note / Case Study
Determining the Fluorescence Limit of Detection for a Given Flourophore
This note works through an experiment to approximately establish a
baseline in terms of the fluorescence limit of detection for a given fluorophore.
App Note / Case Study
The Investigative Power of Multiple Detectors: a Case Study of a Semi-Pure ß-Amylase Extract
This note discusses the analysis of a semi-purified protein mixture containing ß-amylase. Step-by-step, we show how different properties of the proteins elicit a specific response in each detector and how the coupling this data can be qualitatively and quantitatively evaluated.
App Note / Case Study
Utilization of kinITC in AFFINImeter
This note discusses how and when can kinetic information be retrieved from ITC power curves.
App Note / Case Study
Predicting the Compounding Performance of Pressure Sensitive Adhesives (PSA’s)
This note discusses a method for assessing pump-ability and mix-ability of Pressure Sensitive Adhesives during manufacture.
App Note / Case Study
Structural Elucidation of Dextrans and other Polysaccharides using OMNISEC Multi- Detection GPC
A series of dextran samples ranging in molecular weight from about 1– 650 kDa are characterized using OMNISEC. Structural comparisons to other polysaccharides, gum arabic and pectin are presented.
App Note / Case Study
Predicting the Stability of Dispersions with a Yield Stress
This application note shows methodology and data for evaluating the stability of two shower gel (bodywash) products against their capability to suspend bubbles as a product requirement.
App Note / Case Study
Detecting the Presence of Anomolous Large Particles Within Powders Using Laser Diffraction Particle Size Analysis
In this application note, we demonstrate the capability of the Aero S dry dispersion unit and the Mastersizer 3000 to measure small quantities of pharmaceutical materials dosed with large particles and to detect those large, anomalous particles.
App Note / Case Study
Measuring Small Quantities of Dry Powder Using the Aero S and Mastersizer 3000
In this application note, we demonstrate the capability of the Aero S dry dispersion unit and the Mastersizer 3000 to measure small quantities of pharmaceutical materials with good reproducibility and illustrating the dispersion abilities of the Aero S.
App Note / Case Study
Measuring Small Volumes of Nanoparticles Using the Mastersizer 3000 and Hydro SV
This application note discusses the measurement of two nano-sized pigment samples using the Mastersizer 3000 and Hydro SV, highlighting the capability of the technique in resolving small differences in the particle size of the samples.
App Note / Case Study
Aseptic Identification of Polysorbates using Handheld Raman
As polysorbates are reactive to light and air, packaging is usually in thick, dark, amber bottles. This makes the identification process more difficult, as opening the container could compromise the sterility and quality of these materials. Handheld Raman is capable of identifying these materials without any sampling or preparation.
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