Latest App Notes & Case Studies

To accelerate the discovery of new cancer biomarkers and new insights into the genetics of treatment-resistant tumors, it is crucial to gain a deeper understanding of the genomic and epigenomic variations in cancer.

Chinese hamster ovary (CHO) is the cell line of choice in many biotherapeutic production workflows. Yet, in the early stages of drug development, CHO lines require high-performing, chemically defined media optimized for their specific needs.

PFAS, a group of highly stable small molecules full of toxicity that appear in every corner of the globe, demands a comprehensive approach to protect the integrity of our environment. Traditional methods fall short due to the lack of available certified reference standards.

High-volume laboratories must keep analytic instruments running reliably while producing quality data. This means laboratory managers and technicians must ensure their instruments are performing optimally around the clock.

In food safety, chemical manufacturing and environmental testing labs, filtration of the sample and mobile phase prior to analysis helps reduce overall instrument wear and removes any particles that may interfere with the chromatogram.

Targeted sequencing based on NGS offers new perspectives in drug selection for cancer patients. The accuracy of mutation analysis relies on the tumor content of the tissue samples.

In the quest for therapeutic or analytical antibodies, it is crucial to carefully select antibodies based on their kinetics, affinity, specificity and biophysical attributes. Antibody screening plays a pivotal role in identifying cell clones that generate antibodies suited to a specific purpose, often challenging these antibodies with a known antigen.

This app note highlights a highly sensitive method developed for the detection of GalSPH and GluSPH in CSF.

In food safety, chemical manufacturing and environmental testing labs, the need to consistently generate high-quality data means that managers, scientists and technicians must ensure their instruments are performing optimally around the clock.

This application note demonstrates the successful identification of two low-abundance monoclonal antibodies using next-generation protein sequencing.