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Advanced Solutions for Accurate Cell-Free DNA Quality Assessment

3D illustration of a DNA double helix intertwined with floating cells in a blue microscopic environment, representing genetic research and biotechnology
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Cell-free DNA (cfDNA) is a powerful tool in clinical research, enabling the identification of non-invasive biomarkers and possible mutations from various biofluids.


Quality control of cfDNA is essential to the success of downstream workflows, such as next-generation sequencing (NGS), ensuring that any degradation or contamination within the sample is identified.


This application note explores how electrophoretic methods surpass the capabilities of traditional methods to accurately distinguish between cfDNA and contaminating high molecular weight (HMW) DNA, making them ideal for cfDNA quality control.


Download this application note to learn:

  • Why accurate detection and quantification of contaminating HMW DNA is critical for successful NGS
  • How cfDNA assays provide objective assessment of sample quality
  • The advantages of the latest analysis methods for comprehensive cfDNA quality control
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