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mAb Quantitation: Protein A HPLC vs Protein A Bio-Layer Interferometry

mAb Quantitation: Protein A HPLC vs Protein A Bio-Layer Interferometry content piece image

There are currently more than 140 monoclonal antibodies (mAbs) approved by the FDA as biotherapeutic agents, representing the most rapidly growing class of new drugs. Therefore, rapid, accurate and cost-effective quantitation of mAbs is essential for bioprocessing.

Download this app note to discover a technique that: 

  • Accurately quantitates 5%, 10% and 20% mAb breakthrough values
  • Performs at its best at low concentrations with an almost 30-fold lower LoQ
  • Costs 20% lower in comparison to equivalent techniques