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How We Tackle Antibiotic Resistance Now
Article

The fight against antibiotic resistance is real and is something we all have a responsibility in tackling. In fact, Antibiotic resistance kills an estimated 700,000 people each year and has fuelled the re-emergence of illnesses that had become a rarity in many parts of the world.

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Practical Guidance for the Confident Application of Differential Scanning Calorimetry
Article

In this article, we provide practical guidance for the application of differential scanning calorimetry (DSC), a core technique for studying the stability and higher order structure (HOS) of proteins. We explain how DSC works, and highlight good practice for ensuring optimal data quality. The interpretation and value of the resulting data is also discussed.

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Advancing Drug Discovery Through Academic–Industry Collaboration
Article

Genestack recently announced that they were joining the Milner Therapeutics Institute. In light of the announcement, I spoke to Prof. Tony Kouzarides, Director of the Milner Therapeutics Institute and Dr. Misha Kapushesky, Founder and CEO of Genestack, to learn more.

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Targeted Drug Delivery Via Nanoparticles Could Help Repair Transplant Organs
Article

Scientists have designed targeted nanoparticles to aid the therapeutic delivery of drugs directly to organs. This new technique could increase the number of viable organs available for transplantation.

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NMR Spectroscopy: A Brief Guide
Article

Nuclear magnetic resonance spectroscopy is a non-destructive analytical technique that enables interrogation of the nature and structure of organic compounds. It is proving an invaluable tool in food provenance investigation and recent advances to improve analysis speed and sensitivity look set to continue this trend.

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Lipidomics Opens Doors to Understanding Stem Cell Differentiation
Article

It has long been known that the fats we consume in our diet can have an impact on our health. However, their implications on cell differentiation has not previously been understood. We spoke to Professor Ilya Levental about his group's exciting work in this field, the role of lipidomics and how this may affect the future of healthcare.

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Protein Biotherapeutics: Mass Spectrometry Analysis
Article

Mass spectrometry has evolved as a prevailing technique for both the characterization of biotherapeutics and identification of protein variants and post-translational modifications.

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Uncovering the Role of H. pylori in Stomach Cancer
Article

An interdisciplinary team of researchers recently demonstrated the role that H. pylori plays in gastric stem cell renewal. We spoke to lead author, Professor Thomas Meyer from the Max Planck Institute for Infection Biology, to learn more about the study and its wider implications for the future diagnosis and treatment of stomach cancer.

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Types of Biosensors and Evolving Applications: Glucose Monitoring to Personalized Health
Article

Since its origins in the 1960s, the biosensors field has grown to encompass a wide range of sensors, from enzyme-based to immunosensors to DNA biosensors. Along with this, a diverse set of applications have flourished, with biosensors finding roles in food safety, medical diagnostics, and environmental analysis to name just a few.

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Spectroscopic Techniques for Food Analysis to Combat Adulteration and Fraud
Article

Food fraud takes many forms, including adulteration, package tampering, outright counterfeiting of products or ingredients, mislabeling, intentional use of illegal or substandard ingredients, manufacturing shortcuts to lower production costs, and many others. Thanks to modern technology, detecting food fraud is mostly an analytical chemistry exercise, with choice of methodology depending on the quality attribute the food detective is looking for.

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