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A Renaissance for Microflow Liquid Chromatography Mass Spectrometry?
Article

First developed in the 1970s, recent developments are making microflow liquid chromatography techniques more robust – enticing researchers to revisit the opportunities it offers for more sensitive, high-throughput analyses requiring smaller sample volumes than standard flow techniques.

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Synthetic Biology Rewrites the Rules of the Genome
Article

Synthetic biology (SB) is an umbrella term that covers a wide range of scientific applications. In this article we'll explore work aiming to synthesize genes faster than ever before, expand the genetic alphabet and turn DNA into a storage medium. To this end, we interviewed two leading figures in the field, Emily Leproust PhD, CEO of Twist Bioscience and Floyd Romesberg PhD, a Professor of Chemistry at the Scripps Institute.

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Big Data Analysis Approaches for Drug Discovery
Article

Big data has long been a buzzword in drug discovery, but as analysis methods become more sophisticated, its potential is beginning to be realized. We look at some of the latest advances in big data analysis for drug discovery.

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Case Study: Dr. Kaelberer Validates a Neuroepithelial Circuit using Milo
Article

How does the gut talk to the brain? In this new case study from ProteinSimple, we find out how Melanie Maya Kaelberer, a Postdoctoral Associate at Duke University, is using Single-Cell Western platform Milo to answer the question of how the gut can rapidly communicate with cranial nerves.

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Microglia Transmit Pain to the Brain During Stress
Article

Chronic pain is a multifaceted disorder that causes profound disability worldwide. It has long been known that psychological stress contributes to adverse chronic pain outcomes in patients, but it is unclear how this is initiated or amplified by stress. Now, researchers have published results showing that activation of microglia in the mouse spinal cord is responsible for increased pain sensitivity in response to stress.

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Building Blocks for a Greener Future
Article

At a time when plastic use is coming under great scrutiny, what are LEGO, whose foundations are built on plastic products, doing to alleviate the problem? We spoke to Tim Brooks, VP Environmental Responsibility for LEGO Group about their commitment to use sustainable materials in core products and packaging by 2030.

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Mass Spectrometry’s Important Role in Identifying Explosives in the Environment
Article

Explosives, especially when not contained or disposed of correctly, pose a significant hazard to humans, wildlife and the ecosystem. Having the tools to be able to identify their presence and state are therefore key to combating the issue. We spoke to Stanislaw Popiel about the game-changing role that mass spectrometry is playing in the process and some of the challenges that still lie ahead.

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ELN, LIMS, CDS, LES: What’s the Difference?
Article

In this article, we look at the key differences between four common types of informatics systems. CSols Inc. is an independent informatics consultancy, and their Delivery Manager, Geoff Turnbull, will help us answer some important questions on the role these systems play, where they overlap with each other, and why we don’t just have one overarching system to rule them all.

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How Advances in Mass Spectrometry Are Helping the Food and Beverage Industry
Article

Mass spectrometry is an important tool for many industries, not least in ensuring the safety of our food and beverages. Hazards ranging from pesticides, to heavy metals and toxins can be identified using the technology, even if they are only present in minute quantities. Here Jenny Nelson tells us how advances in mass spectrometry have improved analysis potential and the important role it has played and will continue to play in ensuring the safety of the beverage industry.

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Overcoming Challenges in Biopharma: Transformational Innovation is Key
Article

Looking at the industry growth and the complexities of biopharma development, it is no wonder that transformational developments are required to better equip laboratories and operations in biopharma.

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