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Shedding Light on Wine Fraud with NMR Fingerprinting
Article

Wine forgery, including adulteration, counterfeiting (e.g. mislabeling/misrepresentation) and intellectual property infringement, takes place on a global scale, but is on the rise in central Europe. To help in the fight against fraud, the industry are turning to NMR fingerprinting to stamp out the problem.

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Insects – THE New Animal Feed in the EU
Article

The world population increases and so does the need for food. In order to breed more livestock, naturally, more animal feed is necessary but production of protein rich feed, such as soy and fishmeal are damaging the environment. Several alternatives have been proposed but one in particular seems very promising: insects!

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Understanding the Role of BDNF on GABAergic neurotransmission
Article

Researchers have identified a mechanism by which brain-derived neurotrophic factor (BDNF) can suppress GABAergic transmission in hippocampus. In this article, Dr. Rajamani Selvam explains how he and his team achieved these results, and their potential impact on the treatment of neurological disease.

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Discovering Druggable Targets
Article

We recently spoke to Dr Kilian V. M. Huber from the Structural Genomics Consortium & Target Discovery Institute, University of Oxford to find out – ‘What makes a good target?’.

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Single-Cell DNA Sequencing Weaves a Way Towards Personalized Cancer Treatment
Article

High-throughput single-cell analysis has been regularly acclaimed as a transformative technology for sequencing and a huge step towards the goal of personalized medicine. Will Tapestri, a sequencing platform developed by Mission Bio, be the game-changer in DNA analysis we have been waiting for?

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Target Identification & Validation in Drug Discovery
Article

This article highlights the properties of an attractive drug target, outlines the approaches used to identify targets, and discusses the key steps involved in target validation and the benefits and challenges of using siRNA to validate targets.

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Light Sheet Imaging Helps Capture Zebrafish Neural Development
Article

A video showing the birth of an incredible network of neurons in the nervous system of a Zebrafish has won first prize at the Nikon Small World in Motion Awards, which highlight the best in photography and video captured through the microscope lens. We caught up with researchers behind the video to find out more.

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One-Pot Reactions: Synthesizing Natural Product Analogs for Drug Discovery
Article

Scientists have discovered powerful new reactions for the synthesis of nature-inspired privileged structures – one-pot, modular, elegantly designed chemical reactions that could minimize the gap between the chemical and biological space. Their study findings could be a turning point for the discovery of unmet diseases.

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The Advances Powering the CRISPR Revolution
Article

CRISPR-based gene editing has been implemented across the scientific community in the past 5 years. Although CRISPR is relatively easy and efficient compared to previous gene editing methods, researchers are continuing to improve the technology. New advancements are designed to make different types of genetic changes, improve efficiency, and improve delivery of CRISPR for different therapeutic approaches.

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