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Phenotypic Screening – Advances in Technologies and Techniques
Phenotypic screening is gaining new momentum in drug discovery with the hope that this approach will improve the success rate of drug approval. In this article we look at some of the latest screening tools and their applications.
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It’s Alive: Cautious Excitement Meets Claims of First Effective Alzheimer’s Drug
American pharma giant Biogen has announced that its therapeutic compound for Alzheimer’s disease (AD), aducanumab, is to be taken to the FDA for approval. Despite being seemingly killed off after a study in March produced disappointing results, new analysis suggests that aducanumab met its target endpoints.
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Testing Medicines After Brexit: Upholding High QC Standards for Pharmaceuticals
Maintaining robust quality control standards is a key priority for any commercial industry – but for pharmaceutical manufacturers, it can literally be a matter of life and death. The looming Brexit deadline is likely to be seen as a pivotal moment by those operating in the sector. The prospect of the UK leaving the European Union, and the jurisdiction of the EU’s unified single market for medicine regulation, is creating considerable uncertainty for drugmakers.
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Merging With Machines: A Look at Emerging Neuroscience Technologies
In this article, we explore how emerging neurotechnologies are taking us from movement-controlled to mind-controlled machines and from machine extensions of ourselves to machines integrated into ourselves.
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Technology Networks Explores the CRISPR Revolution: An Interview With Professor Jennifer Doudna, Co-developer of CRISPR Genome Editing Technology
Technology Networks spoke with the world-renowned scientist and 2020 Nobel Prize in Chemistry winner Professor Jennifer Doudna, the co-developer of CRISPR genome editing technology.
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Mouse Moms’ Microbiota Lead to Altered Behavior
Research presented at Neuroscience 2019, the flagship conference of the Society for Neuroscience, has highlighted research at the intersection of three fascinating areas: neurodevelopment, the immune system and the gut microbiota.
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Evaluating Detection Methods for Persistent Infection
A pair of recent studies looked at the reliability of clinical observations and bacterial culture versus quantitative PCR (qPCR) in detecting clinically healthy carriers of the bacterium that causes strangles, who pose an infection risk to naïve individuals.
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Is DNA the Next Frontier for Data Storage?
Whether you are an individual consumer, or a large enterprise, data storage is a hassle. However, there may be a new answer; storing our digital data on DNA. To find out more, we spoke to Dr Bill Efcavitch, Co-founder and Chief Scientific Officer of Molecular Assemblies, Inc.
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Helping the Pharmaceutical Industry Tackle the Evolving Challenge of Water Quality
Water plays a vital role in a broad range of processes within the pharmaceutical industry, from its use as a reagent and solvent in drug synthesis, to its utilization in formulation development and analytical testing, all the way through to product packaging and labeling. As a result, pharmaceutical companies must employ a range of treatment and monitoring processes to ensure the impurities present in water do not interfere with its intended use.
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Automation in 2019: Friend or Foe?
Automation has changed the face of many industries, the medical field being no exception. Can man and machine collaborate? New software could ensure that they can work together harmoniously.
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