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Social Bonding and the Brain: Oxytocin’s role in a neural circuit for maternal social behavior
Article

Oxytocin is a neuropeptide important for controlling social behaviors such as pair bonding and parenting. It does this in part by increasing the salience of socially relevant sensory input. However, it has not been clear which neurons in the brain respond to oxytocin, or how oxytocin modifies neural circuits to increase the prominence of social information.

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Optogenetics: Harvesting the Power of Light for Neuronal Control
Article

With accolades like “method of the year” and “breakthrough of the decade,” it’s easy to assume that optogenetics—a scientific technique for turning neurons on and off using light—is, indeed, a game-changing technology.

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Upcoming Helsinki Chemicals Forum Focuses on Critical Chemicals Safety Regulations
Article

Awareness of the risks associated with hazardous chemicals is driving a greater understanding of their long-term effects.

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Anxiety and the ability to predict an outcome
Article

Making decisions is a complex process that is made easier when the outcomes of actions are predictable. Researchers know that people with high anxiety are more likely to interpret unexpected variability as a sign of catastrophe.

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Pittcon 2015 Informatics Wrap-Up
Article

Technology Continues to Impact the Lab; Pittcon Focuses on Workflows, Integration, Meta Data Management and Accelerating Innovation

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Changing Phase of Biomarkers
Article

Discover the current scenario and changing business models of the biomarkers field.

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Geomagnetic visual prosthesis helps blind rats find their way
Article

Navigating a complex environment requires an egocentric representation: a neural signature of how you and your body relate to objects in your visual field. Part of the difficulty in exploring space for those without sight is the challenge of understanding how object positions relate to each other (allocentric representation) and to oneself (egocentric representation).

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Novel mechanism behind Alzheimer’s-related circadian rhythm disruptions
Article

Alzheimer’s disease (AD), a progressive and highly disruptive neurodegenerative condition, leads to a severe decrease in cognitive capabilities. Though the root cause of AD is unclear, it is known that increased levels of amyloid-β—a cleavage product of the amyloid precursor protein (APP)—are associated with development of the disease.

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Cold-shock protein protects against neurodegeneration
Article

In the adult brain, communication between neurons is constantly remodeled by the elimination of old synapses and the formation of new ones; this turnover of synapses is called structural plasticity. Patients with neurodegenerative diseases such as Alzheimer’s disease have fewer synapses compared to normally aging adults, suggesting that their brains have decreased structural plasticity.

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Implanting rewarding memories during sleep
Article

The hippocampus is a neural structure thought to maintain a cognitive map of our surroundings and the activity of some hippocampal neurons reflect when an animal is in a particular location. These ‘place cells’ are thought to represent the cognitive unit which signals the representation of location in space.

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