The Neuroscience of... Creativity
Given the scale of human ingenuity, it has been no mean feat for science to define and study the neural basis of the creative process. In this article, the latest in our “The Neuroscience of…” series, we investigate the research that has attempted to understand where creativity emerges in the brain and why it exists in the first place.
Monoclonal vs Polyclonal Antibodies
Antibodies are immunological proteins that play fundamental roles in host defense against infectious agents such as viruses, bacteria and fungi. Two types of antibodies – polyclonal and monoclonal – provide research scientists with distinct ways to detect or quantify target antigens largely due to differences in specificity and affinity. In this article, we describe polyclonal and monoclonal antibodies in more detail and consider how each type may be used for various applications.
Social Bonding and the Brain: Oxytocin’s role in a neural circuit for maternal social behavior
Oxytocin is a neuropeptide important for controlling social behaviors such as pair bonding and parenting. It does this in part by increasing the salience of socially relevant sensory input. However, it has not been clear which neurons in the brain respond to oxytocin, or how oxytocin modifies neural circuits to increase the prominence of social information.
Optogenetics: Harvesting the Power of Light for Neuronal Control
With accolades like “method of the year” and “breakthrough of the decade,” it’s easy to assume that optogenetics—a scientific technique for turning neurons on and off using light—is, indeed, a game-changing technology.
Upcoming Helsinki Chemicals Forum Focuses on Critical Chemicals Safety Regulations
Awareness of the risks associated with hazardous chemicals is driving a greater understanding of their long-term effects.
Anxiety and the ability to predict an outcome
Making decisions is a complex process that is made easier when the outcomes of actions are predictable. Researchers know that people with high anxiety are more likely to interpret unexpected variability as a sign of catastrophe.
Pittcon 2015 Informatics Wrap-Up
Technology Continues to Impact the Lab; Pittcon Focuses on Workflows, Integration, Meta Data Management and Accelerating Innovation
Changing Phase of Biomarkers
Discover the current scenario and changing business models of the biomarkers field.
Geomagnetic visual prosthesis helps blind rats find their way
Navigating a complex environment requires an egocentric representation: a neural signature of how you and your body relate to objects in your visual field. Part of the difficulty in exploring space for those without sight is the challenge of understanding how object positions relate to each other (allocentric representation) and to oneself (egocentric representation).
Novel mechanism behind Alzheimer’s-related circadian rhythm disruptions
Alzheimer’s disease (AD), a progressive and highly disruptive neurodegenerative condition, leads to a severe decrease in cognitive capabilities. Though the root cause of AD is unclear, it is known that increased levels of amyloid-β—a cleavage product of the amyloid precursor protein (APP)—are associated with development of the disease.
Cold-shock protein protects against neurodegeneration
In the adult brain, communication between neurons is constantly remodeled by the elimination of old synapses and the formation of new ones; this turnover of synapses is called structural plasticity. Patients with neurodegenerative diseases such as Alzheimer’s disease have fewer synapses compared to normally aging adults, suggesting that their brains have decreased structural plasticity.
Implanting rewarding memories during sleep
The hippocampus is a neural structure thought to maintain a cognitive map of our surroundings and the activity of some hippocampal neurons reflect when an animal is in a particular location. These ‘place cells’ are thought to represent the cognitive unit which signals the representation of location in space.