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The Future is Bright for Single-Cell Proteomics: A Report from HUPO 2018
Article

In recent years the genomes, transcriptomes, and epigenomes of multicellular organisms have been captured in a number of high profile organism-wide atlases. Can proteomics measure up to next-generation sequencing (NGS) technologies when it comes to single cell analysis? Here are the highlights from the Human Proteome Organization (HUPO) World Congress summarizing the latest developments in the field of single cell biology.

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Exploring Consciousness with Psychedelics
Article

Chris Timmermann, from The Psychedelic Research group at Imperial College London studies the action of psychedelics on the brain and their potential as therapeutics. This article reviews their research and their implications.

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Calculating a Least Squares Regression Line: Equation, Example, Explanation
Article

Being able to make conclusions about data trends is one of the most important steps in both business and science. Through the magic of least sums regression, and with a few simple equations, we can calculate a predictive model that can let us estimate our data and give us much more power over it. If you want a simple explanation of how to calculate and draw a line of best fit through your data, read on!

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Untargeted Profiling of Metabolites: In Search of Cancer Biomarkers and Antibiotics
Article

When you are examining a predetermined set of metabolites (in other words, when you know what you are looking for), targeted approaches can be adopted. But when a comprehensive profile of all the metabolites in a sample, known and unknown, is required, untargeted technologies are the way to go. Here, we look at how how untargeted metabolomics is helping science discover new biomarkers for cancer and natural antibiotic sources.

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The Genetics of Coffee Consumption
Article

Marilyn Cornelis, of the Feinberg School of Medicine at Northwestern University, has spent years researching how coffee affects our body. In this interview, she explains how coffee affects our brain, interacts with cannabis, and why listening to your body might be the best way to decide how much coffee to drink.

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How Transitioning to Automation in the Lab Improves Patient Outcomes
Article

Integrating new technologies into laboratory workflows can be a complex transition. This article outlines why, when it comes to diagnosing infections, it's an investment worth making.

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Chemical Snapshots and Molecular Maps with Mass Spec Imaging
Article

Mass spectrometry imaging (MSI) is a powerful tool increasingly being used in many fields including cancer research, biomarker discovery and drug development. This article explains why MSI is the technique of choice in many labs, discusses its use in research, and covers how some inherent challenges are being addressed.

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MALDI Imaging Mass Spectrometry (MALDI IMS): A Marriage of Mass Spectrometry and Morphological Spatial Resolution
Article

Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) is a powerful analytical technique that enjoys the sensitivity of mass spectrometry coupled with spatial distribution information.

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Above the Genome: How Epigenetics Influences Cancer and Obesity
Article

Truly understanding how our DNA influences our lives and health sometimes means moving past the DNA sequence. Epigenetics encompasses a group of heritable modifications without changes to the DNA sequence itself. Our epigenetics affects our susceptibility to a staggering number of diseases, including both cancer and obesity.

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Cancers of the Lung and the Rise of Artificial Intelligence
Article

Artificial intelligence (AI) has begun to transform the world of healthcare and researchers across the globe are now dedicated to discovering its potential. This technology has particularly struck a chord with cancer research surrounding early detection, a long-standing concern for the cancer community.

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