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Proteogenomics: The Path to Personalized Medicine?
Proteogenomics - a multiomic discipline which combines gene, protein and RNA data, has potential to give a true systems perspective on the human body. We look at the techniques that enable proteogenomics analysis, and the potential of the field in the clinic to personalize medicine and battle cancer.
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Metabolomics: The Long Journey from Lab to Clinic
Recent improvements in technology are enabling the simultaneous detection and quantitation of large numbers of metabolites from biological samples. Here, we examine the challenges and innovations in metabolomics technologies and find out how these tools are impacting on clinical biomarker discovery.
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Understanding Addiction
We interviewed award-winning neuroscientist and Editor-in-Chief of the Journal of Neuroscience, Prof. Marina Picciotto, to find out about: her career, work-life balance, the importance of good science communication and what she thinks needs to be done to encourage more women to pursue a STEM career.
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Multiomics and Metaproteomics: Why More Is Better In Proteomic Data Analysis
Developments in next-gen multi-omics have made it possible to generate and process massive amounts of data that cover anything from genomic mutations to metabolomic and microbiological processes. However, handling and analyzing all this data continues to present challenges to even the most experienced bioinformatics experts. In this article we explore some of the solutions and advancements in multi-omics and metaproteomics data analysis approaches.
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Faster Progress for Cancer Research Requires FAIRer Access to Health and Research Data
Advances in research mean researchers have access to more data than ever before, but effectively using and sharing this data has become a major challenge in modern research. In this article, Fiona Nielsen, founder of data platform Repositive, explains how data providers can make access to data easier and more secure.
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The Power of Nanopores for Understanding Proteins -Part 1
We spoke to Professor Giovanni Maglia, group leader in chemical biology at the University of Groningen, about the progress he and his team have been making in turning nanopore technology to solving protein questions.
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Cannabis-Infused Edibles Analysis Reveals Inaccurate, Unreliable Labeling
Lab analysis reveals how even well-known cannabis edibles brands are claiming vastly higher potencies than they are delivering in practice.
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VisIt Application Speeds Visualization Workloads and Empowers Global Research
VisIt, an open source application developed at Lawrence Livermore National Laboratory, helps analzye data and turn it into beautiful visualizations. Here, some of the architects of VisIt explain how it has grown to become a data behemoth which benefits research in fields from astrophysics to climate science.
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Cannabis Oil for Epilepsy – What You Need to Know
A small number of studies have shown that adding cannabis oil to existing medication may be effective in devastating, hard-to-treat epilepsy in children and adolescents.
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The Role of Wnt Signaling in Cancer
Aberrant Wnt signaling has also been identified as a key mechanism in cancer biology. This article summarizes both the canonical (β-catenin dependent) and non-canonical (β-catenin independent) signaling pathways. It also highlights the role of Wnt signaling in numerous cancers and discusses novel approaches to targeting the pathway.
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