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Cryo-EM and CX-MS: The Power Couple of Proteomics
Article

An ambitious new workflow has married two cutting-edge proteomic analysis techniques to improve imaging of large protein assemblies. The combination of electron cryo-microscopy (cryo-EM) and cross-linking coupled mass spectrometry (CX-MS) allows deeper interrogation of protein structures to a level of detail that the techniques are incapable of obtaining on their own.

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How to Tell “Fake” Olive Oils from the Genuine Article
Article

With olive oil’s popularity on the increase in recent years, olive oil production and sales have become big business. However, it also opens the industry up to fraudsters looking to profiteer from this trend. To tackle this problem, scientists have been exploiting differences at the chemical level to expose adulterated products.

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Cell Potency: Totipotent vs Pluripotent vs Multipotent Stem Cells
Article

Here we discuss the differences between totipotent, pluripotent, and multipotent stem cells.

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Mass Spectrometry in Biopharmaceutical Discovery
Article

Biotherapeutics now makes up 25% of new drugs approvals. Their efficacy and safety are highly dependent on their structures, which are complex, heterogeneous and subject to modification. Advances in mass spectrometry are allowing more information on higher order structure and new imaging techniques are even providing insights into how biological drugs behave in vivo.

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Why do Humans Have Such Large Brains? Our Study Suggests Ecology Was the Driving Force
Article

Most animals have brains in proportion to their body size – species with larger bodies often have larger brains. But the human brain is almost six times bigger than expected for our bodies.

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The Quest for Exascale: Have the Goal Posts Changed in HPC?
Article

The High-Performance Computing community has in recent years been dominated by the quest for Exascale systems, capable of a billion billion calculations per second. However, the interest in artificial intelligence and machine learning capabilities has pushed exascale off the front of stage. In this article, David Yip, HPC and Storage Business Development Manager at OCF, asks whether the quest for exascale is truly over.

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King of Pop Inspired Moves Means More Visits to the Doc
Article

Neurosurgeons raise awareness of the stresses of extreme dance moves on the spine

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Henrietta Lacks: The Mother of Modern Medicine
Article

A portrait of Henrietta Lacks has recently been unveiled at the Smithsonian’s National Portrait Gallery, to recognize her life and the vital contributions HeLa cells have made to science.

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Novel Collagen Membrane Improves Colon-on-a-Chip Functionality
Article

A microfluidic model of the colon has been built using natural tissue base matrix, which closely mimics the structure and function of the colon.

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One Year on, Scientists Defend Canada’s Anti-Genetic Discrimination Law
Article

The Canadian Genetic Non-Discrimination Act (GNA), introduced last May, made it illegal to require individuals to disclose genetic test results or to compel individuals to undergo genetic tests for any agreement or service. However, a subsequent legal challenge has prompted a robust defense of the act from scientists in the May issue of the Canadian Medical Association Journal (CMAJ).

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