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Mitosis vs. Meiosis
Article

Mitosis and meiosis are two kinds of cell division that are essential to most forms of life on earth. Here we investigate the key differences and similarities between the two processes.

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Emerging Classes of Next-generation Biotherapeutics
Article

We are entering uncharted territory in biopharmaceutical development. Emerging new classes of treatments are harnessing the natural power of viruses and cells and engineering them to fight human diseases. As our arsenal of conventional therapies begins to fail, a new army of biotherapeutics is on the horizon. Here, we look at two new classes of treatments leading the charge.

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Using Supercomputers to Predict Dispersal of Chemicals and Pollutants
Article

Motivated by a deadly chemical attack in Syria, researchers at the University of Texas at San Antonio are pursuing research that may help save lives during an airborne chemical attack. The team used the Stampede2 supercomputer and innovative computer simulation models to replicate the dispersion of the chemical gas released in the Syrian event, which may help improve evacuation speed during future attacks.

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Care in the Community – How Biofilms Improve Bacterial Survival
Article

A single bacterial cell on its own is vulnerable to attack and like many living things they can benefit from safety in numbers. But bacteria take communal living to a whole new level, forming veritable civilizations - the bacterial biofilm.

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'Microdosers' of LSD and Magic Mushrooms are Wiser and More Creative
Article

Researchers just ran the first ever pre-registered scientific study on the microdosing of psychedelics and found some very promising results.

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Overcoming Western Blot Reproducibility Problems
Article

This article outlines key workflow steps to help researchers perform better western blots. By executing best practices in these steps – sample preparation, gel electrophoresis, gel transfer, protein detection, and image analysis – researchers can expect good western blot data.

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High-Throughput LC-MS for Early Drug Screening and Biomarker Detection
Article

In this article, we explore two novel high-throughput analytical methods based on liquid chromatography-mass spectrometry (LC-MS) analysis that can augment early drug screening and biomarker detection in the clinic.

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Liver Spheroids: A Major Step Towards Meaningful In Vitro Testing for Human Hepatotoxicity Potential
Article

The development of new in vitro models to replace in vivo testing has already proven quite successful for certain targets. Among these are models of the immune system and human skin, while in vitro cardiac arrhythmia models are poised to emerge in the near future. Despite this clear progress, an efficient model for liver organ toxicity testing still remains elusive.

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Medical Devices: How to Master New Clinical Evaluation Report Criteria
Article

To achieve regulatory compliance and authorization for sale in Europe, every medical device must be supported by a Clinical Evaluation Report which documents the entire clinical evaluation process. Read on for recommendations on how manufacturers can keep up with the changing regulation landscape.

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Antigenic Drift vs Antigenic Shift
Article

As part of the host-pathogen arms race, viruses are continually evolving to evade the host immune response, be it from previous infection or immunity acquired through vaccination. Here we take a look at the processes of antigenic drift and antigenic shift.

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