Latest Articles

The fight against antibiotic resistance is real and is something we all have a responsibility in tackling. In fact, antibiotic resistance kills an estimated 700,000 people each year and has fuelled the re-emergence of illnesses that had become a rarity in many parts of the world.

Since the launch of the project, patients, caregivers, doctors, cancer centers, regulators and others have been hard at work to drive cancer research and treatment forward in a race to beat the disease.

Based on the analysis of cells, genes, and chemical signals in body fluids, liquid biopsies provide timely, actionable information on disease states while eliminating the high cost and risks of tissue biopsies. Gene amplification through polymerase chain reaction and related techniques offer these benefits with the added advantage of amplifying low-abundance species. This article looks at the state of the art in PCR-based liquid biopsies, including a discussion of the technique's limitations.

In this article, we provide practical guidance for the application of differential scanning calorimetry (DSC), a core technique for studying the stability and higher order structure (HOS) of proteins. We explain how DSC works, and highlight good practice for ensuring optimal data quality. The interpretation and value of the resulting data is also discussed.

We spoke to Darlene to learn about her reasons for studying science, how she transitioned away from the lab and some of her proudest achievements at Agilent.

The imaging of biological samples, or bioimaging, plays a key role in current life science research, enabling scientists to analyze molecules, cells and tissues from a range of living systems.

Following the rapid and striking success of vemurafenib, a MAPK targeting drug used to treat melanoma, interest in this critical cell signalling pathway has exploded.

Genestack recently announced that they were joining the Milner Therapeutics Institute. In light of the announcement, we spoke to Prof. Tony Kouzarides, Director of the Milner Therapeutics Institute and Dr. Misha Kapushesky, Founder and CEO of Genestack, to learn more.

It has long been known that the fats we consume in our diet can have an impact on our health. However, their implications on cell differentiation has not previously been understood. We spoke to Professor Ilya Levental about his group's exciting work in this field, the role of lipidomics and how this may affect the future of healthcare.

Nuclear magnetic resonance spectroscopy is a non-destructive analytical technique that enables interrogation of the nature and structure of organic compounds. It is proving an invaluable tool in food provenance investigation and recent advances to improve analysis speed and sensitivity look set to continue this trend.