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The Hunt for Therapeutic Antibodies
Article

Given the clinical success that antibodies (formerly known as “magic bullets”) have facilitated, the drug discovery field continues to search for new therapeutic candidates. This article highlights several techniques used in the process, and touches on current trends driving the field.

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The Why's and How's of Electronic Health Record Compatibility Testing
Article

Although they have become the core of many workflows related to patient care, a recent survey showed that only 10% of physicians were satisfied with their current Electronic Health Record (EHR) system. Continuous compatibility testing can make EHRs more user friendly. This article will describe the essential procedures a healthcare organization will need to undertake during EHR compatibility testing.

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Establishing Immune Memory to Rabies in the CNS
Article

Researchers from Philadelphia University and Thomas Jefferson University have highlighted how building a strong immune memory response to rabies virus in the brain and spinal cord is key to protecting the CNS against infection.

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How Cloud Computing Has Forever Changed HPC
Article

The recent Supercomputing 2018 conference highlighted clear examples of the potential of cloud-based High Performance Computing. In this article, we explore some of the projects driving the field forward.

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World Yoga Day: Finding the OM in GenOMics
Article

A recent climb in the number of people taking up a regular yoga or meditation practise has seen the terms “downward dog” and “tree pose” enter the everyday vocabulary of many. Today, on World Yoga Day, people come together across the world to celebrate the unity that yoga brings. However, from a scientific perspective, what evidence exists that supports the benefits of a regular yoga and meditation practise?

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Emerging Technologies in Combating Foodborne Illness
Article

Rapid and accurate detection of foodborne pathogens is essential to prevent foodborne illnesses and to mitigate the associated economic losses. We take a look at some of the technological advances that are helping to make this happen.

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Pharmaceutical R&D Powered by MALDI Mass Spectrometry Imaging
Article

In order to design and develop new pharmaceutical compounds, the distribution of drugs and their metabolites in tissues must be determined. The emergence of advanced mass spectrometry techniques, such as MALDI imaging, have been pivotal in advancing the field.

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Cell Metabolism and Cancer
Article

It’s almost 100 years since Otto Warburg’s observation that cancer cells metabolize glucose in a manner that is distinct from that of cells in normal tissues. Yet, we still don’t fully understand why. In the years since, significant effort and resource has focused on understanding cancer-specific metabolic changes. Today, attention is also turning to the metabolic interaction between a tumor and its host.

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Frontal Lobe Paradox: Where People Have Brain Damage But Don't Know It
Article

Humans have big brains and our frontal lobes, just behind the forehead, are particularly huge. Injuries to this part of the brain often happen after blows to the head or a stroke. Paradoxically, some people with frontal lobe injuries can seem unaffected – until they’ve been carefully evaluated.

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