Return From Extinction
The prospect of "reviving" an extinct species – or a, genetic hybrid version of it – is moving closer to reality thanks to the sophistication of genome engineering technologies. In this article, sit down with Professor George Church to learn about his plans to "de-extinct" the woolly mammoth.
TRON’s CoVigator Offers an Unseen Perspective of SARS-CoV-2
In this article, we explore how the Corona Virus Navigator (CoVigator) NGS pipeline is being used to identify non-synonymous mutations in the SARS-CoV-2 spike protein.
NMR Spectroscopy Principles, Interpreting an NMR Spectrum and Common Problems
Nuclear magnetic resonance (NMR) spectroscopy is a physicochemical technique used to obtain structural information about molecules. In this article, we consider how it works, what it tells you and where it is used.
Team Reverses the Clinical Signs of Alzheimer’s Disease in Mice
In a study published in Genome Medicine, Dr. Patrick Aloy, head of the structural bioinformatics and network biology laboratory at IRB Barcelona and colleagues report that they have successfully reversed the clinical signs of Alzheimer's disease in mice by repurposing four existing drugs that are currently approved to treat high blood pressure and inflammation.
Identifying Novel Drug Targets for Neurodegeneration
During this year’s ELRIG Drug Discovery Meeting, Prof. Paul Brennan from the University of Oxford, discussed recent progress to develop drug compounds against novel targets in neuroinflammatory and sub-cellular organelle dysfunction pathways.
An Introduction to Five Psychedelics: Psilocybin, DMT, LSD, MDMA and Ketamine
Interest in the therapeutic potential of psychedelics, having lain relatively dormant in the face of stigma and heavy regulations for decades, has reignited in the last ten years. Landmark studies showing these compounds’ effectiveness in treating some mood disorders have kickstarted a wave of clinical research, with well over 100 separate trials now investigating psychedelics’ health applications.
Digitized Lateral Flow Tests Can Transform How We Think About Patient Generated Health Data
Patient generated health data is a hot topic in healthcare, with connected technology driving a shift towards patient-centric care. Phil Groom argues that, after the pandemic, digitized lateral flow testing must become a key part of this movement.
A Next-Generation SARS-CoV-2 Vaccine
A naturally occurring nanoparticle yields a new type of vaccine that offers broad-acting protection against emerging SARS-CoV-2 variants. With further development, the approach may lead to a pan-coronavirus vaccine.
An Introduction to Culturing Bacteria
The ability to grow microbes is an essential step in being able to utilize their power, identify harmful culprits and advance our understanding and capabilities. In this article, we consider what bacterial culture is, factors affecting culture conditions, common problems and some of the numerous applications.
Progress Towards a Mucosal Vaccine for Pneumonia
In a new study, researchers describe a subunit mucosal vaccine that induces broadly protective immunity against Klebsiella pneumoniae strains. Technology Networks interviewed author Jay Kolls to learn more about the findings and their significance.