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Lipidomics: A Rising Star in “OMICS” Research
ArticleFrom medicine to make-up: until recently, a common misconception was that lipids are simply fat molecules, however, recent advances in technologies used to dissect and study lipid profiles prove that this is not the whole truth.
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Pluripotent Stem Cells in Drug Discovery: Can We Stem the Tide of Unsuccessful Drugs?
ArticleStem cells were first discovered in human cord blood in 1978. Why would we think they can be of more help now? This article delves into reasons behind the sudden interest in stem cells, and highlights how they can be used to advance drug discovery.
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The Science of Why so Many People Believe in Psychic Powers
ArticleYou would think that instances of proven psychic fraud over the years would weaken the credibility of psychic claims.
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Addressing Controversy in ADHD: An Interview with Russell A. Barkley, PhD
ArticleWe interviewed Russell A. Barkley, PhD, an internationally recognized expert on attention-deficit hyperactivity disorder (ADHD), to gain an insight into the disorder, its portrayal in the media and the future of ADHD research.
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How Genomics is Shaping Advanced Therapeutics
ArticleGenomics technologies are guiding the development of advanced therapy medicinal products, i.e. gene-based, cell-based, and tissue-engineered approaches. This article highlights the progress, challenges and impact of this interdisciplinary branch of medicine.
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Realizing the Potential of Top-down Proteomics
Article
Having grown beyond early ‘proof-of-principle’ studies, top-down proteomics is now extensively used to analyze intact proteins in numerous applications. Here, we discuss how the top-down proteomics approach emerged, reasons underpinning its success, and highlight some of the most exciting current developments.
Recent Advances in Liquid Biopsy for Cancer
ArticleLiquid biopsies for cancer search for evidence of disease biomarkers, the most common of which include circulating tumor cells, cell-free nucleic acids, exosomes, proteins and phosphoproteins. Read on for insights on advances in the field that could revolutionize clinical oncology practice.
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UK Lung Cancer Diagnostic Services: Time to Step Up
ArticleThe UK’s national health system needs to take a hard look at their priorities and procedures to ensure that rapid advances in molecular diagnostics in lung cancer are translated into a practical service for all patients, according to a report launched at the British Thoracic Oncology Group Annual Conference.
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Overcoming the Identification Bottleneck in Untargeted Metabolomics: Combining Technological and Software Innovations
ArticleUntargeted metabolomics approaches are allowing previously unreported insights into the pathogenesis of disease. However, identifying the large numbers of unknown and structurally diverse metabolites typically present in biological samples has proven to be a major bottleneck. Fortunately, recent advances in technology and software are helping to overcome this challenge.
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ROCKbusting Huntington’s and Probing Parkinson’s
ArticleAt the Society for Neuroscience (SfN) conference last held in November 2018 in San Diego, a truly frightening number of posters were presented over nine sessions. In this article we look in-depth at posters shared by Charles River Laboratories, highlighting research into Huntington's Disease and Parkinson's Disease.
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