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Latest Articles

A Closer Look at Pharmacokinetics
Article

In this article, we will learn about the four main stages of pharmacokinetics – absorption, distribution, metabolism and elimination (ADME) and discuss the factors that influence them.

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Using LIMS for Data Visualization
Article

In any laboratory setting, data can rapidly accumulate. Presenting that data in processed, visual formats can help users better understand and utilize that data. In this article, we take a deep dive into how data visualization tools have become a key facet of LIMS systems and how to AI can assist in the visualization process.

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Exploring Human Biology and Disease With Organoid Models
Article

Advances in cell culture techniques and stem cell technology have enabled the generation of organoids – three-dimensional aggregations of cells capable of recapitulating the structure and physiology of human organs in extraordinary detail. Technology Networks recently interviewed Soumita Das, associate professor at the University of California San Diego, to learn about the organoid models her team is developing.

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Improving Drug Discovery With Organoid-Based “Phase 0” Testing
Article

Technology Networks recently had the pleasure of speaking with Soumita Das, associate professor at the University of California San Diego, to learn more about her work with organoids and some of the research activities at the HUMANOID™ Center of Research Excellence.

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An Overview of Next-Generation Sequencing
Article

Over the last 56 years, researchers have been developing methods and technologies to assist in the determination of nucleic acid sequences in biological samples. Our ability to sequence DNA and RNA accurately has had a great impact in numerous research fields. This article discusses what next-generation sequencing (NGS) is, advances in the technology and its applications.

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An Introduction to PCR
Article

Polymerase chain reaction (PCR) is a technique that has revolutionized the world of molecular biology and beyond. In this article, we will discuss a brief history of PCR and its principles, highlighting the different types of PCR and the specific purposes to which they are being applied.

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Liquid Chromatography – Including HPLC, UHPLC and LCxLC
Article

Liquid chromatography (LC) is a technique used to separate and analyze mixtures of chemical components in solution, to determine if a specific component is present and if so, how much of it is there. In this article we explore how LC works, how the technique has evolved, LC data interpretation and strengths and limitations.

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ICP-OES – ICP Chemistry, ICP-OES Analysis, Strengths and Limitations
Article

Inductively coupled plasma-optical emission spectroscopy (ICP-OES) is an analytical technique that is used to identify the atomic composition of a sample. In this article we will explore how the technique works, what it tells us, strengths, limitations and common problems, and how it compares to other techniques in this analytical niche.

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ICP-MS — ICP-MS Instrumentation, ICP-MS Analysis, Strengths and Limitations
Article

Inductively coupled plasma mass spectrometry (ICP-MS) is a flexible chemical analysis method that can be tailored to meet the demands of a wide variety of industries. In this article, we explore how it works, what it tells us, it's strengths and limitations and how it compares to other techniques in this analytical space.

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Gas Chromatography – How a Gas Chromatography Machine Works, How To Read a Chromatograph and GCxGC
Article

In this article, we take a look at what gas chromatography is, how it works and how to interpret output data. Its combination with mass spectrometry and the use of multiple dimensions are considered, and strengths, limitations and common problems are discussed.

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