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Mass Analyzers for Mass Spectrometry
At the heart of any mass spectrometer is the mass analyzer. This component takes the ionized masses and separates them based on their mass-to-charge ratio (m/z). In this article, we consider some of the common types of mass analyzers, their advantages and disadvantages.
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The Ras Pathway and Cancer: Regulation, Challenges and Therapeutic Progress
In normal health, Ras signaling is central to the regulation of intracellular signaling networks involved in cell proliferation, growth and survival. Like many cellular signaling pathways, however, the Ras-related cascade has a dark side. Mutations in the RAS gene itself, or in upstream or downstream regulators, can push the pathway into a constitutively active, cancer-inducing state.
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Gas Chromatography
In this article, we bring together resources from the across the site on gas chromatography, how it works, its pairing with downstream techniques and what its applications are.
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Collaboration Is the Future of Science—Technology Will Make That Happen
Part of what has enabled collaborations to emerge relatively smoothly over recent years, and especially the past year, has been a growing trend toward digital transformation. In this article, we explore how digital collaboration will pave the way to a new era of drug development.
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DNA Repair Hotspots and “Super-Agers”: An Interview With Fred “Rusty” Gage
Fred “Rusty” Gage is president of the Salk Institute for Biological Studies. After his recent plenary at the British Neuroscience Association’s Festival of Neuroscience, we spoke with Gage about his research into how our DNA repairs itself and how Alzheimer's disease causes neurons to undergo and identity crisis.
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A Step Closer to Orally-Delivered Insulin for Diabetes
A new technology developed within the Trabolsi Research Group at NYU Abu Dhabi (NYUAD) is a step closer to an oral delivery system for insulin therapy that could replace traditional subcutaneous injections. Technology Networks spoke with the research team to find out more.
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Lateral Flow Testing Beyond COVID-19
Before 2020, the words “lateral flow” meant little to anyone outside the scientific community. Now, thanks to COVID-19, lateral flow is no longer an unknown. In this article, we explore the future of the technology.
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How South Africa CHPC Responded to Unprecedented Computing Needs To Address the COVID-19 Pandemic
When South Africa went into lockdown on March 26, 2020, due to COVID-19, the country’s computing needs vastly outgrew the resources provided by Lengau and the OpenStack Production Cloud. In this article, we explore how the South Africa Center for High Performance Computing responded.
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Top Industrialization Challenges of Gene Therapy Manufacturing
Manufacturing and scale-up of industrialized processes to manufacture gene therapy products are accompanied by many challenges that must be overcome to succeed in the marketplace. This article explores some of the fundamental manufacturing challenges in more detail.
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CD8+ T Cells
T cell lymphocytes play a critical role in cell-mediated processes that underlie adaptive immunity. In this article, we focus on CD8+ T cells by characterizing their immunological phenotypes and the processes behind their cell-mediated immune functions.
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