The scale of the U.S. opioid crisis continues to put forensic toxicology laboratories under intense pressure to meet demanding workloads with limited resources. Laboratories therefore need screening workflows that can process large volumes of samples quickly and efficiently, while accelerating the delivery of accurate and reliable results.READ MORE
A clinical trial testing a "mosaic" HIV vaccine is due to commence in September. The trial is pertinent considering a recent UNAIDS report expressed concerns that the pace of progress in reducing new HIV infections has slowed. This article discusses the plans for the trial and the current status of vaccine research in the field.READ MORE
Unsurprisingly, as the proteomics field has grown over recent years, in parallel, so has the size and complexity of the molecules that scientists want to study. The latest addition to the structural biologist's toolbox, cross-linking mass spectrometry (XL-MS), is helping researchers achieve these goals. In this article, we explore the current status of XL-MS with insights from two experts in the field, Professor Andrea Sinz and Dr Alexander Leitner.READ MORE
At the BNA’s Festival of Neuroscience, we were lucky enough to sit down with leading neuroscientists to discuss their work. In this interview, Professor Ileana Hanganu-Opatz describes the mechanisms important for cognitive development and the ways in which they can malfunction.READ MORE
Automation of cell counting and characterization has revolutionized hematology analysis. This article delves into the evolution of automated white blood cell differential count technology, discuses the role of electrical impedance, and looks to optical technologies and their role in the future of blood characterization.READ MORE
Fully characterizing how the brain goes awry in disease states depends heavily upon the ability to visualize specific neuron subtypes. Thankfully, neuroscience has been revolutionized by microscopy tools such as SIM, dSTORM, and STED. In this article, we explore how these techniques are fueling the field's progress.
Here we will take a deep dive into the world of modern medicinal chemistry and learn how scientists are continuously innovating to find drug candidates and get the best ones to market and into your hands.
Great hope has been placed on organ-on-chip models to provide a complex and predictive in vitro models that can recapitulate the human drug response. How far can they go? This article delves into whether organ-on-chips can live up to expectations, and in particular, whether they can do it alone.READ MORE
Genetic analysis is now a common part of diagnosis or treatment for many conditions, and targeted treatments based on specific genetic variants have made personalized medicine a reality. Research has shown that most of the genetic knowledge we have is based on the genomes of a select group of individuals. This article explores how using more diverse genomic databases can help tackle healthcare inequalities.READ MORE
How can you treat something if you don’t know what the problem is? This is the first challenge for medics and vets, one for which diagnostic testing holds the key. But when the disease you want to test for is endemic, it can raise some additional challenges - the all important negative controls.READ MORE