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A Controversial World-first: Gene-Edited Human Babies
Article

A Chinese scientist, He Jiankui, has claimed that he helped make the world-first gene-edited babies: two twin baby girls. Reportedly, he used CRISPR-Cas9 to edit embryos for seven couples during IVF fertility treatment, and engineered the embryos to possess resistance to HIV infection. He Jiankui, from the Southern University of Science and Technology, is now facing investigation over whether the experiment was illegal.

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One-Pot Reactions: Synthesizing Natural Product Analogs for Drug Discovery
Article

Scientists have discovered powerful new reactions for the synthesis of nature-inspired privileged structures – one-pot, modular, elegantly designed chemical reactions that could minimize the gap between the chemical and biological space. Their study findings could be a turning point for the discovery of unmet diseases.

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The Advances Powering the CRISPR Revolution
Article

CRISPR-based gene editing has been implemented across the scientific community in the past 5 years. Although CRISPR is relatively easy and efficient compared to previous gene editing methods, researchers are continuing to improve the technology. New advancements are designed to make different types of genetic changes, improve efficiency, and improve delivery of CRISPR for different therapeutic approaches.

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Drug Screening: Cellular proliferation assay performed inside a mouse
Article

Although many new cellular assays entered the drug discovery scene over the course of the last decades, we still lack a predictable tool when it comes to selecting compounds or cell lines for xenograft testing. What is lacking?

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What Does a Big-Storage Future Look Like in HPC?
Article

Samsung's recent announcement of 30TB drives is part of a wider trend within high-performance computing (HPC) towards big storage. But, as HPC consultant Laurence Horrocks-Barlow writes, these huge storage capacities present unique challenges and opportunities for organizations on a budget.

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Mitosis vs. Meiosis: Key Differences, Chart and Venn Diagram
Article

Mitosis and meiosis are two kinds of cell division that are essential to most forms of life on earth. Here we investigate the key differences and similarities between the two processes.

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Emerging Classes of Next-generation Biotherapeutics
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We are entering uncharted territory in biopharmaceutical development. Emerging new classes of treatments are harnessing the natural power of viruses and cells and engineering them to fight human diseases. As our arsenal of conventional therapies begins to fail, a new army of biotherapeutics is on the horizon. Here, we look at two new classes of treatments leading the charge.

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Using Supercomputers to Predict Dispersal of Chemicals and Pollutants
Article

Motivated by a deadly chemical attack in Syria, researchers at the University of Texas at San Antonio are pursuing research that may help save lives during an airborne chemical attack. The team used the Stampede2 supercomputer and innovative computer simulation models to replicate the dispersion of the chemical gas released in the Syrian event, which may help improve evacuation speed during future attacks.

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Care in the Community – How Biofilms Improve Bacterial Survival
Article

A single bacterial cell on its own is vulnerable to attack and like many living things they can benefit from safety in numbers. But bacteria take communal living to a whole new level, forming veritable civilizations - the bacterial biofilm.

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'Microdosers' of LSD and Magic Mushrooms are Wiser and More Creative
Article

Researchers just ran the first ever pre-registered scientific study on the microdosing of psychedelics and found some very promising results.

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