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qPCR vs dPCR: Choosing the Right PCR Technology To Suit Your Experimental Needs

Gloved hand holding a 96 well plate in front of a screen displaying qPCR amplification curves.
Credit: iStock

Quantitative PCR (qPCR) and digital PCR (dPCR) are powerful tools for nucleic acid detection and quantification, each with distinct strengths. Both technologies play vital roles in genomics research, from monitoring infectious diseases in wastewater to detecting rare mutations in liquid biopsies. Understanding their differences can help you make informed decisions for your specific experimental needs.


This article breaks down the advantages of each method, including cost considerations, throughput capabilities and sensitivity. Continue reading to find out which PCR platform is best suited to advance your research.

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