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Landmark Study Solves Structure of Dementia Protein

Article   Jul 05, 2017 | Adam Tozer PhD, Technology Networks

Structure of Tau Filaments from Alzheimer’s Brain Solved by Cryo-EM

Tau filament structures, rendered in blue and white. In the background, a photomicrograph of a Bodian silver-stain preparation shows a neuron from the cerebral cortex of an individual affected by Alzheimer disease. The cytoplasm around the nucleus contains a flame-shaped neurofibrillary tangle. The Tau filaments appear to wrap around the neuron.

Adam Tozer PhD

Science Writer



The Evolution of Proteomics - Dr Richard Scheltema


Richard Scheltema is an assistant professor at Utrecht University where he heads up the Scheltema laboratory within the wider context of the group of Albert Heck. The research group focuses on mass spectrometry (MS) based structural proteomics, for which they develop advanced liquid chromatography-mass spectrometry (LC-MS/MS) platforms and analysis software.


Native Mass Spectrometry: A Glimpse Into the Machinations of Biology


The question perhaps is not when native mass spectrometry can be used; but rather, when can’t it be used? Today, the applications are broad-reaching and diverse. This article shares insights from innovators in the field who have helped establish this incredibly useful analytical technique.


MeTooSTEM: A Mission to End Sexual Harassment in STEM


In the wake of the "Me Too" (or #MeToo) movement, a spotlight has been cast on an additional obstacle that deters many individuals, particularly women, from working in STEM – the astonishingly high incidence of sexual harassment. In this article, we look at the extent of the issue and speak with some of the women that are working tirelessly to combat sexual harassment in STEM through a variety of organizations.



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