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Blog

Automated Microfluidic Systems for Gene Editing
Blog

Recently, Oxford Genetics and Sphere Fluidics announced a multi-partner collaboration to expedite the development of automated microfluidic systems for rapid and high-throughput gene editing in mammalian cells. We spoke with Emily Leproust, PhD, CEO of Twist Biosciences, and other collaborators from the partnership to discuss the background of this announcement and the need for automated systems in gene editing.

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Tailoring Flow Reactor Equipment to the Particular Chemistry at Hand
Blog

We recently spoke to André de Vries from InnoSyn BV to learn more about the considerations to make when scaling up chemical processes. He outlines the advantages of flow chemistry over batch processes and discusses how to design and manufacture flow reactors for any type of chemistry.

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Take a Good Book Around
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Our recent social media poll on "book recommendations for scientists" provided an incredible response. We decided to collate this information and give you the perfect excuse to treat yourself to a new read. Enjoy!

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Breath Test for Cancer: Biomarker Screening is Underway
Blog

The thought that compounds in the breath could be measured and assessed to diagnose different aspects of pathology is an exciting prospect. To learn more about the breathalyzer platform being used in clinical trials to detect early cancer biomarkers, we spoke to Chris Claxton, head of investor relations at Owlstone Medical.

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Superficial Radiation Therapy: A Non-surgical Treatment for Non-melanoma Skin Cancers
Blog

Skin cancer can be broadly split in to two types: melanoma and non-melanoma. The most common non-melanomas include basal cell carcinoma and squamous cell carcinoma, for which the main treatment is surgery. However, other non-surgical options are emerging, including superficial radiation therapy (SRT), a unique type of photon radiotherapy.

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The Vision for Multi-organ Human-on-a-Chip Models
Blog

The development of organ-on-a-chip models aims to reduce the (expensive) high drug failure rates that exist in clinical trials. A Florida biotech firm recently reported that their multi-organ “human-on-a-chip” system maintains cellular viability over 28 days in serum-free conditions, using a pumpless system. To learn more about the vision for multi-organ “human-on-a-chip” models, we caught up with James Hickman, Chief Science Officer of Hesperos Inc.

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Is Off-the-Shelf Immunotherapy the Way Forward?
Blog

An “off-the-shelf” immuno-oncology product has been developed whereby T cells are derived from healthy donors, bypassing limitations related to high pricing and limited market access.

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FISH Probes Approved for Targeted Genome Analysis in Cancer
Blog

Recently, the FDA granted de novo classification for eight fluorescence in situ hybridisation (FISH) probes for myelodysplastic syndromes and acute myeloid leukaemia. We spoke with Steve Chatters, Director of Medical Affairs at Oxford Gene Technology, to learn more about the application of FISH probes in modern medicine.

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The Booming Business of Neurotoxin Therapy
Blog

Botulinum neurotoxins are widely used in both therapeutic and cosmetic applications, but Ipsen says that their new rBoNT-E toxin is a step up from compounds based on the much more widely used serotype A toxin. We spoke to Ipsen Senior Vice President Neurosciences R&D, Philippe Picaut, to find out more.

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Harnessing AI in a Battle Against Aging
Blog

A recently announced collaboration between Juvenescence, Ltd., and NetraMark Corp. has yielded a new joint venture, NetraPharma, which aims to fight aging-related conditions. We spoke with NetraMark founder Dr. Joseph Geraci to find out more about how the process of targeting and treating neurodegenerative disorders will be radically changed by AI.

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